Zinc in PDB 2d74: Crystal Structure of Translation Initiation Factor AIF2BETAGAMMA Heterodimer

The structure of Crystal Structure of Translation Initiation Factor AIF2BETAGAMMA Heterodimer, PDB code: 2d74 was solved by M.Sokabe, M.Yao, N.Sakai, S.Toya, I.Tanaka, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	68.467, 76.177, 98.210, 90.00, 90.00, 90.00
R / Rfree (%)	24.4 / 29

The binding sites of Zinc atom in the Crystal Structure of Translation Initiation Factor AIF2BETAGAMMA Heterodimer (pdb code 2d74). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Translation Initiation Factor AIF2BETAGAMMA Heterodimer, PDB code: 2d74:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Translation Initiation Factor AIF2BETAGAMMA Heterodimer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Translation Initiation Factor AIF2BETAGAMMA Heterodimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:40.2 occ:1.00 SG A:CYS76 2.1 45.8 1.0 SG A:CYS73 2.1 39.8 1.0 SG A:CYS64 2.1 40.0 1.0 SG A:CYS61 2.1 39.0 1.0 CB A:CYS61 3.1 45.3 1.0 CB A:CYS64 3.2 39.3 1.0 CB A:CYS73 3.2 39.1 1.0 CB A:CYS76 3.6 50.3 1.0 N A:CYS64 3.6 40.9 1.0 CA A:CYS64 4.0 40.5 1.0 N A:CYS76 4.0 51.4 1.0 CA A:CYS76 4.4 51.5 1.0 CA A:CYS61 4.5 45.2 1.0 CD1 A:TYR75 4.5 57.7 1.0 CA A:CYS73 4.6 40.7 1.0 C A:CYS64 4.7 40.0 1.0 C A:ASN63 4.8 41.1 1.0 N A:GLY77 4.8 50.3 1.0 CB A:ASN63 4.8 44.3 1.0 N A:GLY65 4.8 40.1 1.0 CB A:TYR75 4.9 52.4 1.0 ND2 A:ASN63 4.9 44.7 1.0 C A:CYS61 5.0 45.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Translation Initiation Factor AIF2BETAGAMMA Heterodimer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Translation Initiation Factor AIF2BETAGAMMA Heterodimer within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1002 b:71.9 occ:1.00 SG B:CYS107 2.1 67.6 1.0 SG B:CYS131 2.1 73.0 1.0 SG B:CYS110 2.1 68.8 1.0 SG B:CYS128 2.1 72.0 1.0 CB B:CYS107 2.8 65.5 1.0 CB B:CYS128 2.8 70.7 1.0 O B:CYS110 3.1 79.8 1.0 CB B:CYS131 3.1 74.0 1.0 CB B:CYS110 3.7 74.3 1.0 N B:CYS131 4.0 75.2 1.0 C B:CYS110 4.0 77.4 1.0 N B:CYS110 4.1 75.2 1.0 CA B:CYS131 4.1 74.5 1.0 CG2 B:VAL109 4.1 72.7 1.0 CA B:CYS110 4.2 75.4 1.0 CA B:CYS107 4.3 65.1 1.0 CA B:CYS128 4.3 72.3 1.0 OG B:SER112 4.4 77.2 1.0 CB B:SER112 4.6 76.9 1.0 N B:GLY132 4.7 74.3 1.0 CB B:ALA133 4.7 75.1 1.0 C B:CYS107 4.9 66.1 1.0 C B:CYS131 4.9 74.9 1.0 N B:ALA133 4.9 73.6 1.0

M.Sokabe, M.Yao, N.Sakai, S.Toya, I.Tanaka. Structure of Archaeal Translational Initiation Factor 2 Betagamma-Gdp Reveals Significant Conformational Change of the Beta-Subunit and Switch 1 Region. Proc.Natl.Acad.Sci.Usa V. 103 13016 2006.
ISSN: ISSN 0027-8424
PubMed: 16924118
DOI: 10.1073/PNAS.0604165103