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Atomistry » Zinc » PDB 1y8f-1yj6 » 1y8j » |
Zinc in PDB 1y8j: Crystal Structure of Human Nep Complexed with An Imidazo[4,5- C]Pyridine InhibitorEnzymatic activity of Crystal Structure of Human Nep Complexed with An Imidazo[4,5- C]Pyridine Inhibitor
All present enzymatic activity of Crystal Structure of Human Nep Complexed with An Imidazo[4,5- C]Pyridine Inhibitor:
3.4.24.11; Protein crystallography data
The structure of Crystal Structure of Human Nep Complexed with An Imidazo[4,5- C]Pyridine Inhibitor, PDB code: 1y8j
was solved by
S.Sahli,
B.Frank,
W.B.Schweizer,
F.Diederich,
D.Blum-Kaelin,
J.D.Aebi,
H.J.Bohm,
C.Oefner,
G.E.Dale,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Nep Complexed with An Imidazo[4,5- C]Pyridine Inhibitor
(pdb code 1y8j). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Nep Complexed with An Imidazo[4,5- C]Pyridine Inhibitor, PDB code: 1y8j: Zinc binding site 1 out of 1 in 1y8jGo back to Zinc Binding Sites List in 1y8j
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Nep Complexed with An Imidazo[4,5- C]Pyridine Inhibitor
Mono view Stereo pair view
Reference:
S.Sahli,
B.Frank,
W.B.Schweizer,
F.Diederich,
D.Blum-Kaelin,
J.D.Aebi,
H.J.Bohm,
C.Oefner,
G.E.Dale.
Second-Generation Inhibitors For the Metalloprotease Neprilysin Based on Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-Ray Crystal Structure Analysis Helv.Chim.Acta V. 88 731 2005.
Page generated: Wed Dec 16 03:13:54 2020
ISSN: ISSN 0018-019X DOI: 10.1002/HLCA.200590051 |
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