Zinc in PDB 1y8f: Solution Structure of the MUNC13-1 C1-Domain

The binding sites of Zinc atom in the Solution Structure of the MUNC13-1 C1-Domain (pdb code 1y8f). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of the MUNC13-1 C1-Domain, PDB code: 1y8f:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of the MUNC13-1 C1-Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of the MUNC13-1 C1-Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:0.0 occ:1.00 ND1 A:HIS567 2.3 0.0 1.0 SG A:CYS600 2.4 0.0 1.0 SG A:CYS616 2.5 0.0 1.0 SG A:CYS597 2.5 0.0 1.0 HB2 A:GLU599 2.6 0.0 1.0 HA A:HIS567 2.8 0.0 1.0 H A:CYS600 3.2 0.0 1.0 CE1 A:HIS567 3.2 0.0 1.0 CG A:HIS567 3.3 0.0 1.0 HB3 A:HIS567 3.3 0.0 1.0 HB2 A:CYS616 3.4 0.0 1.0 HB2 A:CYS600 3.4 0.0 1.0 HE1 A:HIS567 3.4 0.0 1.0 CB A:CYS600 3.5 0.0 1.0 CB A:HIS567 3.6 0.0 1.0 CB A:CYS616 3.6 0.0 1.0 HG3 A:GLU599 3.6 0.0 1.0 N A:CYS600 3.7 0.0 1.0 CA A:HIS567 3.7 0.0 1.0 CB A:GLU599 3.7 0.0 1.0 CB A:CYS597 3.8 0.0 1.0 H A:ASN568 3.8 0.0 1.0 HB3 A:CYS597 3.9 0.0 1.0 HG12 A:VAL602 4.0 0.0 1.0 HB2 A:CYS597 4.0 0.0 1.0 CG A:GLU599 4.1 0.0 1.0 CA A:CYS600 4.2 0.0 1.0 H A:GLU599 4.2 0.0 1.0 C A:GLU599 4.3 0.0 1.0 HB3 A:GLU599 4.3 0.0 1.0 HA A:CYS616 4.3 0.0 1.0 NE2 A:HIS567 4.4 0.0 1.0 HB3 A:CYS616 4.4 0.0 1.0 HB3 A:CYS600 4.4 0.0 1.0 CD2 A:HIS567 4.4 0.0 1.0 CA A:GLU599 4.4 0.0 1.0 CA A:CYS616 4.5 0.0 1.0 N A:HIS567 4.6 0.0 1.0 N A:ASN568 4.6 0.0 1.0 HB2 A:HIS567 4.6 0.0 1.0 N A:GLU599 4.7 0.0 1.0 C A:HIS567 4.7 0.0 1.0 CD A:GLU599 4.7 0.0 1.0 OE2 A:GLU599 4.7 0.0 1.0 HA A:CYS600 4.9 0.0 1.0 CG1 A:VAL602 4.9 0.0 1.0 H A:GLY601 4.9 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of the MUNC13-1 C1-Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of the MUNC13-1 C1-Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn702 b:0.0 occ:1.00 ND1 A:HIS605 2.3 0.0 1.0 SG A:CYS608 2.3 0.0 1.0 SG A:CYS580 2.4 0.0 1.0 SG A:CYS583 2.5 0.0 1.0 HB3 A:CYS580 2.9 0.0 1.0 HB2 A:CYS580 2.9 0.0 1.0 CB A:CYS580 2.9 0.0 1.0 HB2 A:HIS605 2.9 0.0 1.0 HB2 A:CYS608 3.0 0.0 1.0 CB A:CYS608 3.2 0.0 1.0 H A:HIS605 3.2 0.0 1.0 CE1 A:HIS605 3.2 0.0 1.0 H A:CYS583 3.3 0.0 1.0 HB3 A:GLU582 3.3 0.0 1.0 CG A:HIS605 3.3 0.0 1.0 HE1 A:HIS605 3.4 0.0 1.0 HB3 A:CYS608 3.4 0.0 1.0 CB A:HIS605 3.6 0.0 1.0 N A:HIS605 4.0 0.0 1.0 CB A:CYS583 4.0 0.0 1.0 N A:CYS583 4.1 0.0 1.0 HB3 A:CYS583 4.2 0.0 1.0 NE2 A:HIS605 4.4 0.0 1.0 CB A:GLU582 4.4 0.0 1.0 H A:GLY585 4.4 0.0 1.0 HB2 A:CYS604 4.4 0.0 1.0 CD2 A:HIS605 4.4 0.0 1.0 CA A:CYS580 4.4 0.0 1.0 HB3 A:HIS605 4.5 0.0 1.0 H A:GLU582 4.5 0.0 1.0 CA A:HIS605 4.5 0.0 1.0 H A:CYS608 4.6 0.0 1.0 CA A:CYS608 4.6 0.0 1.0 CA A:CYS583 4.6 0.0 1.0 HA A:CYS604 4.6 0.0 1.0 HB2 A:GLU582 4.7 0.0 1.0 OE1 A:GLU582 4.7 0.0 1.0 CD A:GLU582 4.8 0.0 1.0 HB2 A:CYS583 4.8 0.0 1.0 HA A:CYS580 4.8 0.0 1.0 HA A:CYS608 4.9 0.0 1.0 HA3 A:GLY585 5.0 0.0 1.0

N.Shen, O.Guryev, J.Rizo. Intramolecular Occlusion of the Diacylglycerol-Binding Site in the C1 Domain of MUNC13-1. Biochemistry V. 44 1089 2005.
ISSN: ISSN 0006-2960
PubMed: 15667202
DOI: 10.1021/BI0476127