Zinc in PDB 1r8u: uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex

The binding sites of Zinc atom in the uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex (pdb code 1r8u). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex, PDB code: 1r8u:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn440 b:0.0 occ:1.00 NE2 B:HIS362 2.1 0.0 1.0 SG B:CYS379 2.3 0.0 1.0 SG B:CYS384 2.3 0.0 1.0 SG B:CYS366 2.3 0.0 1.0 CD2 B:HIS362 2.8 0.0 1.0 HD2 B:HIS362 2.8 0.0 1.0 HB2 B:CYS366 3.0 0.0 1.0 CB B:CYS366 3.2 0.0 1.0 CE1 B:HIS362 3.3 0.0 1.0 HD2 B:LYS388 3.5 0.0 1.0 HB3 B:CYS366 3.6 0.0 1.0 CB B:CYS384 3.7 0.0 1.0 CB B:CYS379 3.7 0.0 1.0 HB3 B:CYS384 3.7 0.0 1.0 HE1 B:HIS362 3.8 0.0 1.0 HB2 B:CYS379 3.8 0.0 1.0 HB2 B:CYS384 3.9 0.0 1.0 HH11 B:ARG369 4.0 0.0 1.0 HB3 B:LEU381 4.0 0.0 1.0 CG B:HIS362 4.1 0.0 1.0 O B:LEU381 4.1 0.0 1.0 HZ3 B:LYS388 4.1 0.0 1.0 HB3 B:CYS379 4.2 0.0 1.0 H B:LEU381 4.2 0.0 1.0 ND1 B:HIS362 4.3 0.0 1.0 HD2 B:ARG369 4.5 0.0 1.0 CD B:LYS388 4.5 0.0 1.0 CA B:CYS366 4.6 0.0 1.0 HA B:ALA363 4.6 0.0 1.0 HD3 B:LYS388 4.7 0.0 1.0 HA B:CYS366 4.7 0.0 1.0 NH1 B:ARG369 4.7 0.0 1.0 HZ1 B:LYS388 4.7 0.0 1.0 HA B:CYS379 4.8 0.0 1.0 H B:CYS384 4.8 0.0 1.0 C B:LEU381 4.8 0.0 1.0 NZ B:LYS388 4.8 0.0 1.0 CA B:CYS379 4.9 0.0 1.0 H B:SER380 4.9 0.0 1.0 CA B:CYS384 5.0 0.0 1.0 CB B:LEU381 5.0 0.0 1.0

Zinc binding site 2 out of 3 in the uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn441 b:0.0 occ:1.00 NE2 B:HIS393 2.1 0.0 1.0 SG B:CYS397 2.3 0.0 1.0 SG B:CYS403 2.3 0.0 1.0 SG B:CYS408 2.3 0.0 1.0 HD2 B:HIS393 2.7 0.0 1.0 CD2 B:HIS393 2.7 0.0 1.0 HB2 B:CYS397 3.0 0.0 1.0 CB B:CYS397 3.1 0.0 1.0 HB3 B:CYS408 3.2 0.0 1.0 HB3 B:CYS397 3.3 0.0 1.0 CB B:CYS408 3.3 0.0 1.0 CE1 B:HIS393 3.3 0.0 1.0 HB B:VAL405 3.5 0.0 1.0 HB2 B:CYS408 3.5 0.0 1.0 CB B:CYS403 3.6 0.0 1.0 HB2 B:CYS403 3.7 0.0 1.0 HE1 B:HIS393 3.8 0.0 1.0 HB3 B:CYS403 3.9 0.0 1.0 CG B:HIS393 4.0 0.0 1.0 HA B:MET394 4.2 0.0 1.0 HB2 B:ALA399 4.3 0.0 1.0 ND1 B:HIS393 4.3 0.0 1.0 CB B:VAL405 4.5 0.0 1.0 H B:ALA399 4.5 0.0 1.0 CA B:CYS397 4.6 0.0 1.0 H B:VAL405 4.7 0.0 1.0 HG23 B:VAL405 4.7 0.0 1.0 CA B:CYS408 4.8 0.0 1.0 HA B:CYS397 4.8 0.0 1.0 H B:ALA409 4.8 0.0 1.0 HG21 B:VAL405 4.8 0.0 1.0 O B:VAL405 4.9 0.0 1.0 CA B:CYS403 4.9 0.0 1.0 HA B:CYS403 5.0 0.0 1.0 CG2 B:VAL405 5.0 0.0 1.0

Zinc binding site 3 out of 3 in the uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of uc(Nmr) Structure of Cbp TAZ1/CITED2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn442 b:0.0 occ:1.00 NE2 B:HIS417 2.1 0.0 1.0 SG B:CYS426 2.3 0.0 1.0 SG B:CYS421 2.3 0.0 1.0 SG B:CYS429 2.3 0.0 1.0 HB3 B:CYS421 2.6 0.0 1.0 HE1 B:HIS417 2.7 0.0 1.0 CE1 B:HIS417 2.7 0.0 1.0 HB3 B:CYS426 2.7 0.0 1.0 CB B:CYS426 2.8 0.0 1.0 CB B:CYS421 2.9 0.0 1.0 HB2 B:CYS426 2.9 0.0 1.0 H B:CYS429 3.2 0.0 1.0 HB2 B:CYS421 3.3 0.0 1.0 HB B:VAL428 3.3 0.0 1.0 CD2 B:HIS417 3.4 0.0 1.0 HA B:TRP418 3.8 0.0 1.0 CB B:CYS429 3.8 0.0 1.0 HD2 B:HIS417 3.8 0.0 1.0 HB2 B:CYS429 3.8 0.0 1.0 ND1 B:HIS417 4.0 0.0 1.0 H B:VAL428 4.0 0.0 1.0 HG11 B:VAL428 4.1 0.0 1.0 N B:CYS429 4.1 0.0 1.0 CG B:HIS417 4.3 0.0 1.0 CA B:CYS421 4.3 0.0 1.0 CB B:VAL428 4.3 0.0 1.0 CA B:CYS426 4.3 0.0 1.0 HB3 B:CYS429 4.5 0.0 1.0 HE3 A:MET256 4.6 0.0 1.0 CG1 B:VAL428 4.6 0.0 1.0 CA B:CYS429 4.7 0.0 1.0 HG13 B:VAL428 4.7 0.0 1.0 C B:CYS421 4.7 0.0 1.0 HD1 B:HIS417 4.8 0.0 1.0 O B:HIS417 4.8 0.0 1.0 HA B:CYS421 4.8 0.0 1.0 CA B:TRP418 4.8 0.0 1.0 HA B:CYS426 4.8 0.0 1.0 O B:CYS421 4.8 0.0 1.0 HD1 B:TRP418 4.9 0.0 1.0 N B:VAL428 4.9 0.0 1.0 C B:CYS426 4.9 0.0 1.0 HD2 B:PRO427 5.0 0.0 1.0 H B:CYS421 5.0 0.0 1.0 CA B:VAL428 5.0 0.0 1.0

R.N.De Guzman, M.A.Martinez-Yamout, H.J.Dyson, P.E.Wright. Interaction of the TAZ1 Domain of the Creb-Binding Protein with the Activation Domain of CITED2: Regulation By Competition Between Intrinsically Unstructured Ligands For Non-Identical Binding Sites. J.Biol.Chem. V. 279 3042 2004.
ISSN: ISSN 0021-9258
PubMed: 14594809
DOI: 10.1074/JBC.M310348200