Zinc in PDB 1r5x: Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome

The structure of Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome, PDB code: 1r5x was solved by X.I.Ambroggio, D.C.Rees, R.J.Deshaies, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.19 / 2.30
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	76.161, 76.161, 92.124, 90.00, 90.00, 120.00
R / Rfree (%)	26.3 / 30.8

The binding sites of Zinc atom in the Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome (pdb code 1r5x). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome, PDB code: 1r5x:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn122 b:55.8 occ:1.00 NE2 A:HIS69 2.0 28.1 1.0 NE2 A:HIS67 2.0 42.0 1.0 OD2 A:ASP80 2.1 50.0 1.0 OD1 A:ASP80 2.3 53.5 1.0 CG A:ASP80 2.5 51.5 1.0 CE1 A:HIS67 2.8 41.4 1.0 CE1 A:HIS69 2.9 28.3 1.0 CD2 A:HIS69 3.0 27.6 1.0 CD2 A:HIS67 3.2 39.5 1.0 O A:HOH133 3.2 54.8 1.0 OG A:SER77 3.5 48.9 1.0 CB A:ASP80 4.0 52.6 1.0 ND1 A:HIS67 4.0 39.6 1.0 ND1 A:HIS69 4.0 27.5 1.0 CB A:SER77 4.1 49.6 1.0 CG A:HIS69 4.1 28.0 1.0 CG A:HIS67 4.2 37.7 1.0 N A:SER77 4.4 50.4 1.0 OE2 A:GLU22 4.5 44.3 1.0 CD1 A:ILE93 4.8 30.6 1.0 CA A:ASP80 4.9 53.3 1.0 CA A:SER77 4.9 50.4 1.0 O A:HOH145 5.0 58.2 1.0

Zinc binding site 2 out of 2 in the Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn122 b:51.7 occ:1.00 NE2 B:HIS67 2.1 37.1 1.0 NE2 B:HIS69 2.2 26.5 1.0 OD1 B:ASP80 2.2 49.6 1.0 OD2 B:ASP80 2.2 46.0 1.0 CG B:ASP80 2.5 46.6 1.0 CD2 B:HIS67 2.9 32.5 1.0 O B:HOH141 3.0 49.2 1.0 CD2 B:HIS69 3.1 23.6 1.0 CE1 B:HIS69 3.2 25.9 1.0 CE1 B:HIS67 3.2 35.0 1.0 OG B:SER77 3.6 49.8 1.0 CB B:ASP80 4.0 47.1 1.0 CG B:HIS67 4.1 34.5 1.0 CB B:SER77 4.2 49.6 1.0 ND1 B:HIS67 4.2 35.5 1.0 CG B:HIS69 4.2 25.3 1.0 ND1 B:HIS69 4.3 26.5 1.0 N B:SER77 4.5 49.9 1.0 OE2 B:GLU22 4.5 48.1 1.0 CD1 B:ILE93 4.6 24.6 1.0 O B:HOH145 4.8 72.2 1.0 CA B:ASP80 4.9 48.3 1.0 CA B:SER77 5.0 50.2 1.0

X.I.Ambroggio, D.C.Rees, R.J.Deshaies. Jamm: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome. Plos Biol. V. 2 E2 2004.
ISSN: ISSN 1544-9173
PubMed: 14737182
DOI: 10.1371/JOURNAL.PBIO.0020002