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Atomistry » Zinc » PDB 1oht-1p0f » 1oq5 » |
Zinc in PDB 1oq5: Carbonic Anhydrase II in Complex with Nanomolar InhibitorEnzymatic activity of Carbonic Anhydrase II in Complex with Nanomolar Inhibitor
All present enzymatic activity of Carbonic Anhydrase II in Complex with Nanomolar Inhibitor:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase II in Complex with Nanomolar Inhibitor, PDB code: 1oq5
was solved by
A.Weber,
A.Casini,
A.Heine,
D.Kuhn,
C.T.Supuran,
A.Scozzafava,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1oq5:
The structure of Carbonic Anhydrase II in Complex with Nanomolar Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase II in Complex with Nanomolar Inhibitor
(pdb code 1oq5). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase II in Complex with Nanomolar Inhibitor, PDB code: 1oq5: Zinc binding site 1 out of 1 in 1oq5Go back to Zinc Binding Sites List in 1oq5
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase II in Complex with Nanomolar Inhibitor
Mono view Stereo pair view
Reference:
A.Weber,
A.Casini,
A.Heine,
D.Kuhn,
C.T.Supuran,
A.Scozzafava,
G.Klebe.
Unexpected Nanomolar Inhibition of Carbonic Anhydrase By Cox-2-Selective Celecoxib: New Pharmacological Opportunities Due to Related Binding Site Recognition. J.Med.Chem. V. 47 550 2004.
Page generated: Mon Jan 25 16:11:07 2021
ISSN: ISSN 0022-2623 PubMed: 14736236 DOI: 10.1021/JM030912M |
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