Zinc in PDB 1my2: Crystal Titration Experiment (Ampa Complex Control)

The structure of Crystal Titration Experiment (Ampa Complex Control), PDB code: 1my2 was solved by R.Jin, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.73 / 1.80
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	114.540, 164.103, 47.395, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 24.4

The binding sites of Zinc atom in the Crystal Titration Experiment (Ampa Complex Control) (pdb code 1my2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 5 binding sites of Zinc where determined in the Crystal Titration Experiment (Ampa Complex Control), PDB code: 1my2:
Jump to Zinc binding site number: 1; 2; 3; 4; 5;

Zinc binding site 1 out of 5 in the Crystal Titration Experiment (Ampa Complex Control)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Titration Experiment (Ampa Complex Control) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:20.0 occ:1.00 OE2 B:GLU166 2.1 20.4 1.0 OE1 A:GLU42 2.1 20.5 1.0 NE2 A:HIS46 2.3 20.6 1.0 CD B:GLU166 2.8 22.4 1.0 OE1 B:GLU166 2.8 22.5 1.0 CD A:GLU42 3.1 21.7 1.0 O B:HOH868 3.2 8.3 1.0 CE1 A:HIS46 3.2 22.8 1.0 CD2 A:HIS46 3.3 21.8 1.0 OE2 A:GLU42 3.4 19.8 1.0 N B:SER168 4.2 16.8 1.0 CG B:GLU166 4.3 19.7 1.0 CD2 A:LEU241 4.3 22.6 1.0 ND1 A:HIS46 4.3 19.9 1.0 CG A:GLU42 4.4 17.9 1.0 CG A:HIS46 4.4 21.4 1.0 O B:ALA165 4.6 15.2 1.0 CB B:SER168 4.7 15.8 1.0 CB A:GLU42 4.7 16.3 1.0 CA B:SER168 4.8 15.8 1.0 CB B:GLU166 4.8 20.2 1.0 C B:PRO167 4.9 17.9 1.0 CA B:GLU166 5.0 19.1 1.0 CA B:PRO167 5.0 17.6 1.0

Zinc binding site 2 out of 5 in the Crystal Titration Experiment (Ampa Complex Control)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Titration Experiment (Ampa Complex Control) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn702 b:26.7 occ:1.00 NE2 B:HIS23 2.1 24.7 1.0 O B:HOH830 2.1 25.0 1.0 OE2 B:GLU30 2.3 23.9 1.0 CD B:GLU30 2.9 22.8 1.0 OE1 B:GLU30 3.0 21.4 1.0 CD2 B:HIS23 3.0 24.4 1.0 CE1 B:HIS23 3.1 24.4 1.0 CD B:LYS20 4.0 23.7 1.0 NZ B:LYS20 4.1 23.7 1.0 CG B:HIS23 4.2 25.6 1.0 ND1 B:HIS23 4.2 24.6 1.0 CG B:GLU30 4.4 24.3 1.0 O B:GLU30 4.5 21.5 1.0 CE B:LYS20 4.7 23.4 1.0 CD1 B:LEU26 4.9 34.8 1.0

Zinc binding site 3 out of 5 in the Crystal Titration Experiment (Ampa Complex Control)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Titration Experiment (Ampa Complex Control) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn704 b:24.3 occ:1.00 NE2 B:HIS46 2.1 17.2 1.0 OE1 B:GLU42 2.2 21.8 1.0 O B:HOH721 2.2 18.8 1.0 CE1 B:HIS46 3.0 18.8 1.0 CD B:GLU42 3.0 20.0 1.0 CD2 B:HIS46 3.1 18.6 1.0 OE2 B:GLU42 3.2 22.1 1.0 CD2 B:LEU241 3.6 19.7 1.0 OE1 B:GLN244 3.9 38.9 1.0 CE B:LYS45 4.0 22.4 1.0 NZ B:LYS45 4.0 19.5 1.0 ND1 B:HIS46 4.1 19.8 1.0 CG B:HIS46 4.2 17.3 1.0 CG B:GLU42 4.3 18.4 1.0 CB B:GLU42 4.7 13.3 1.0 CD2 B:LEU246 5.0 26.9 1.0

Zinc binding site 4 out of 5 in the Crystal Titration Experiment (Ampa Complex Control)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Titration Experiment (Ampa Complex Control) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn703 b:30.5 occ:1.00 OD2 C:ASP65 2.3 24.0 1.0 OD1 C:ASP65 2.7 25.5 1.0 CG C:ASP65 2.8 24.4 1.0 CB C:ASP67 4.3 34.5 1.0 CB C:ASP65 4.3 22.9 1.0 CG2 C:THR68 4.8 27.0 1.0 OD2 C:ASP67 4.8 41.1 1.0 OG1 C:THR68 5.0 23.5 1.0

Zinc binding site 5 out of 5 in the Crystal Titration Experiment (Ampa Complex Control)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Titration Experiment (Ampa Complex Control) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn705 b:53.2 occ:1.00 OE1 C:GLU42 2.4 31.8 1.0 NE2 C:HIS46 2.5 38.2 1.0 CD C:GLU42 3.3 32.8 1.0 CE1 C:HIS46 3.3 38.0 1.0 CD2 C:HIS46 3.5 36.8 1.0 CE C:LYS45 3.6 41.3 1.0 NZ C:LYS45 3.7 43.5 1.0 OE2 C:GLU42 3.7 35.2 1.0 CD2 C:LEU241 4.2 20.8 1.0 ND1 C:HIS46 4.5 37.4 1.0 CG C:GLU42 4.6 29.6 1.0 CG C:HIS46 4.6 36.2 1.0 CD C:LYS45 4.8 39.2 1.0 CB C:GLU42 4.9 25.9 1.0

R.Jin, E.Gouaux. Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GLUR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GLUR2 S1S2 in the Crystal. Biochemistry V. 42 5201 2003.
ISSN: ISSN 0006-2960
PubMed: 12731861
DOI: 10.1021/BI020632T