Zinc in PDB 1fbv: Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases

All present enzymatic activity of Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases:
6.3.2.19;

The structure of Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases, PDB code: 1fbv was solved by N.Zheng, P.Wang, P.D.Jeffrey, N.P.Pavletich, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 2.90
Space group	P 41 3 2
Cell size a, b, c (Å), α, β, γ (°)	219.000, 219.000, 219.000, 90.00, 90.00, 90.00
R / Rfree (%)	22.7 / 26.2

The binding sites of Zinc atom in the Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases (pdb code 1fbv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases, PDB code: 1fbv:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:62.2 occ:1.00 SG A:CYS381 2.2 57.8 1.0 SG A:CYS384 2.3 61.9 1.0 SG A:CYS404 2.3 61.3 1.0 SG A:CYS401 2.3 64.2 1.0 CB A:CYS381 2.9 61.4 1.0 CB A:CYS401 3.2 62.9 1.0 CB A:CYS384 3.3 66.5 1.0 CB A:CYS404 3.3 62.7 1.0 N A:CYS384 3.5 65.4 1.0 N A:CYS401 3.8 59.2 1.0 CA A:CYS401 4.0 61.3 1.0 CA A:CYS384 4.0 64.5 1.0 CB A:ILE383 4.2 64.0 1.0 O A:CYS401 4.2 63.7 1.0 CA A:CYS381 4.3 63.1 1.0 N A:CYS404 4.3 61.0 1.0 CA A:CYS404 4.4 60.1 1.0 C A:ILE383 4.5 65.5 1.0 C A:CYS401 4.5 62.2 1.0 O A:CYS381 4.6 62.5 1.0 C A:CYS381 4.6 63.4 1.0 CA A:ILE383 4.7 65.5 1.0 ND2 A:ASN387 4.8 63.7 1.0 N A:ILE383 4.8 66.6 1.0 CB A:ASN387 4.8 56.7 1.0 C A:CYS384 4.9 65.8 1.0 CG2 A:ILE383 4.9 59.6 1.0 N A:ALA385 4.9 65.0 1.0 O A:ASN387 5.0 59.9 1.0

Zinc binding site 2 out of 2 in the Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of A Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin- Protein Ligases within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:70.2 occ:1.00 ND1 A:HIS398 2.0 73.9 1.0 SG A:CYS416 2.2 64.6 1.0 SG A:CYS396 2.3 70.6 1.0 SG A:CYS419 2.3 76.7 1.0 CE1 A:HIS398 2.7 73.5 1.0 CB A:CYS416 3.0 67.2 1.0 CG A:HIS398 3.1 72.6 1.0 CB A:CYS396 3.4 67.0 1.0 N A:CYS419 3.6 77.0 1.0 CB A:CYS419 3.6 78.1 1.0 CB A:HIS398 3.8 64.7 1.0 NE2 A:HIS398 3.8 72.6 1.0 CD2 A:HIS398 4.0 72.0 1.0 CA A:CYS419 4.1 77.9 1.0 CB A:PHE418 4.3 73.8 1.0 N A:HIS398 4.3 58.2 1.0 CA A:CYS416 4.4 68.4 1.0 C A:CYS419 4.6 80.3 1.0 C A:PHE418 4.7 76.1 1.0 CA A:HIS398 4.7 58.4 1.0 N A:GLY397 4.7 67.2 1.0 N A:PHE418 4.8 74.0 1.0 CA A:CYS396 4.8 68.4 1.0 CA A:PHE418 4.8 74.9 1.0 CG2 A:ILE393 4.9 58.0 1.0 C A:CYS416 4.9 67.0 1.0 CB A:ILE393 5.0 55.2 1.0 O A:CYS419 5.0 81.2 1.0

N.Zheng, P.Wang, P.D.Jeffrey, N.P.Pavletich. Structure of A C-Cbl-UBCH7 Complex: Ring Domain Function in Ubiquitin-Protein Ligases. Cell(Cambridge,Mass.) V. 102 533 2000.
ISSN: ISSN 0092-8674
PubMed: 10966114
DOI: 10.1016/S0092-8674(00)00057-X