Atomistry » Zinc » PDB 1evr-1f62 » 1ez2
Atomistry »
  Zinc »
    PDB 1evr-1f62 »
      1ez2 »

Zinc in PDB 1ez2: Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate.

Enzymatic activity of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate.

All present enzymatic activity of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate.:
3.1.8.1;

Protein crystallography data

The structure of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate., PDB code: 1ez2 was solved by H.M.Holden, M.M.Benning, F.M.Raushel, S.-B.Hong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.90
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 129.400, 91.000, 69.200, 90.00, 91.60, 90.00
R / Rfree (%) n/a / n/a

Zinc Binding Sites:

The binding sites of Zinc atom in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate. (pdb code 1ez2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate., PDB code: 1ez2:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 1ez2

Go back to Zinc Binding Sites List in 1ez2
Zinc binding site 1 out of 4 in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:18.3
occ:1.00
 NE2 A:HIS55 1.7 7.0 1.0
NE2 A:HIS57 2.0 18.7 1.0
O A:HOH1551 2.2 19.2 1.0
OQ2 A:KCX169 2.3 14.5 1.0
OD2 A:ASP301 2.3 13.3 1.0
CE1 A:HIS55 2.8 14.7 1.0
CD2 A:HIS55 2.8 17.2 1.0
CE1 A:HIS57 3.0 25.4 1.0
CX A:KCX169 3.0 14.6 1.0
CD2 A:HIS57 3.1 16.3 1.0
CG A:ASP301 3.1 35.6 1.0
OQ1 A:KCX169 3.2 27.2 1.0
OD1 A:ASP301 3.3 17.8 1.0
ZN A:ZN402 3.3 23.8 1.0
C6 A:DII1403 3.7 24.9 0.7
C4 A:DII1403 3.9 18.7 0.7
ND1 A:HIS55 3.9 10.5 1.0
CG A:HIS55 3.9 9.0 1.0
CE1 A:HIS230 4.0 26.6 1.0
CG2 A:VAL101 4.1 8.3 1.0
ND1 A:HIS57 4.1 21.7 1.0
CG A:HIS57 4.2 21.4 1.0
NE2 A:HIS230 4.2 22.7 1.0
NZ A:KCX169 4.2 19.2 1.0
O1 A:DII1403 4.4 19.9 0.7
CB A:ASP301 4.5 16.6 1.0
C5 A:DII1403 4.7 27.0 0.7
O3 A:DII1403 5.0 34.3 0.7
CA A:ASP301 5.0 11.4 1.0

Zinc binding site 2 out of 4 in 1ez2

Go back to Zinc Binding Sites List in 1ez2
Zinc binding site 2 out of 4 in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn402

b:23.8
occ:1.00
 OQ1 A:KCX169 1.8 27.2 1.0
NE2 A:HIS230 2.0 22.7 1.0
O A:HOH1551 2.1 19.2 1.0
ND1 A:HIS201 2.3 27.7 1.0
O1 A:DII1403 2.5 19.9 0.7
CX A:KCX169 2.8 14.6 1.0
CE1 A:HIS230 2.9 26.6 1.0
CD2 A:HIS230 3.1 24.9 1.0
OQ2 A:KCX169 3.2 14.5 1.0
CG A:HIS201 3.2 17.7 1.0
CE1 A:HIS201 3.3 21.1 1.0
ZN A:ZN401 3.3 18.3 1.0
CB A:HIS201 3.4 13.2 1.0
CE1 A:HIS55 3.7 14.7 1.0
NE2 A:HIS55 3.8 7.0 1.0
P1 A:DII1403 3.8 28.4 0.7
ND1 A:HIS230 4.1 26.2 1.0
NE1 A:TRP131 4.1 13.0 1.0
NZ A:KCX169 4.1 19.2 1.0
C7 A:DII1403 4.1 29.6 0.7
CG A:HIS230 4.2 30.1 1.0
OD1 A:ASP301 4.2 17.8 1.0
CD2 A:HIS201 4.3 23.6 1.0
NE2 A:HIS201 4.3 30.1 1.0
CA A:HIS201 4.4 21.1 1.0
C4 A:DII1403 4.4 18.7 0.7
O3 A:DII1403 4.7 34.3 0.7
CD1 A:TRP131 4.7 16.7 1.0
CE A:KCX169 4.8 18.7 1.0
CG A:ASP301 4.9 35.6 1.0
OD2 A:ASP301 4.9 13.3 1.0
ND1 A:HIS55 5.0 10.5 1.0

Zinc binding site 3 out of 4 in 1ez2

Go back to Zinc Binding Sites List in 1ez2
Zinc binding site 3 out of 4 in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn401

b:16.8
occ:1.00
 NE2 B:HIS55 1.8 6.0 1.0
NE2 B:HIS57 2.1 19.4 1.0
O B:HOH2609 2.1 13.6 1.0
OQ1 B:KCX169 2.2 16.2 1.0
OD2 B:ASP301 2.3 13.4 1.0
CE1 B:HIS55 2.8 6.4 1.0
CD2 B:HIS55 2.9 12.5 1.0
CE1 B:HIS57 3.0 16.1 1.0
CX B:KCX169 3.1 15.4 1.0
CD2 B:HIS57 3.1 11.7 1.0
CG B:ASP301 3.1 27.4 1.0
OD1 B:ASP301 3.3 19.6 1.0
ZN B:ZN402 3.3 19.2 1.0
OQ2 B:KCX169 3.4 23.4 1.0
C1 B:DII2403 3.9 37.7 0.7
ND1 B:HIS55 3.9 7.9 1.0
CG B:HIS55 4.0 9.1 1.0
CG2 B:VAL101 4.0 13.3 1.0
CE1 B:HIS230 4.1 18.6 1.0
ND1 B:HIS57 4.2 15.3 1.0
CG B:HIS57 4.2 19.4 1.0
NE2 B:HIS230 4.2 17.0 1.0
C3 B:DII2403 4.2 32.5 0.7
C2 B:DII2403 4.3 25.4 0.7
NZ B:KCX169 4.4 23.9 1.0
CB B:ASP301 4.4 14.3 1.0
O1 B:DII2403 4.4 21.8 0.7
C7 B:DII2403 4.9 22.4 0.7
O2 B:DII2403 4.9 65.8 0.7
CA B:ASP301 5.0 11.6 1.0

Zinc binding site 4 out of 4 in 1ez2

Go back to Zinc Binding Sites List in 1ez2
Zinc binding site 4 out of 4 in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Diisopropylmethyl Phosphonate. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn402

b:19.2
occ:1.00
 O B:HOH2609 2.0 13.6 1.0
NE2 B:HIS230 2.0 17.0 1.0
ND1 B:HIS201 2.0 20.0 1.0
OQ2 B:KCX169 2.1 23.4 1.0
O1 B:DII2403 2.6 21.8 0.7
CE1 B:HIS201 2.9 20.1 1.0
CX B:KCX169 3.0 15.4 1.0
CE1 B:HIS230 3.0 18.6 1.0
CD2 B:HIS230 3.1 21.0 1.0
CG B:HIS201 3.1 18.3 1.0
OQ1 B:KCX169 3.3 16.2 1.0
ZN B:ZN401 3.3 16.8 1.0
CB B:HIS201 3.5 7.5 1.0
P1 B:DII2403 3.7 28.9 0.7
CE1 B:HIS55 3.8 6.4 1.0
C7 B:DII2403 3.8 22.4 0.7
NE2 B:HIS55 4.0 6.0 1.0
NE2 B:HIS201 4.1 19.9 1.0
OD1 B:ASP301 4.1 19.6 1.0
ND1 B:HIS230 4.2 15.2 1.0
NE1 B:TRP131 4.2 15.6 1.0
CG B:HIS230 4.2 28.3 1.0
CD2 B:HIS201 4.2 16.2 1.0
NZ B:KCX169 4.3 23.9 1.0
CA B:HIS201 4.4 17.8 1.0
C1 B:DII2403 4.5 37.7 0.7
O2 B:DII2403 4.6 65.8 0.7
CE B:KCX169 4.6 18.6 1.0
CD1 B:TRP131 4.8 17.1 1.0
CG B:ASP301 4.8 27.4 1.0
OD2 B:ASP301 4.8 13.4 1.0
O3 B:DII2403 4.9 51.1 0.7

Reference:

M.M.Benning, S.B.Hong, F.M.Raushel, H.M.Holden. The Binding of Substrate Analogs to Phosphotriesterase. J.Biol.Chem. V. 275 30556 2000.
ISSN: ISSN 0021-9258
PubMed: 10871616
DOI: 10.1074/JBC.M003852200
Page generated: Sun Oct 13 00:35:17 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy