Zinc in PDB 7fav: Crystal Structure of Rubella Protease

The structure of Crystal Structure of Rubella Protease, PDB code: 7fav was solved by J.P.Quek, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.37 / 1.64
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	60.243, 60.243, 173.86, 90, 90, 90
R / Rfree (%)	18 / 19.9

The binding sites of Zinc atom in the Crystal Structure of Rubella Protease (pdb code 7fav). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Rubella Protease, PDB code: 7fav:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Rubella Protease


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Rubella Protease within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1409 b:34.5 occ:1.00 NE2 A:HIS1088 2.1 22.6 1.0 SG A:CYS1037 2.3 22.7 1.0 SG A:CYS1040 2.4 20.2 1.0 SG A:CYS1034 2.4 28.7 1.0 CE1 A:HIS1088 2.9 26.2 1.0 CD2 A:HIS1088 3.2 21.7 1.0 CB A:CYS1034 3.3 30.5 1.0 CB A:CYS1037 3.4 24.4 1.0 CB A:CYS1040 3.5 18.7 1.0 N A:CYS1037 3.5 23.4 1.0 CA A:CYS1037 3.9 23.9 1.0 N A:CYS1040 4.0 19.1 1.0 C A:GLY1036 4.0 26.6 1.0 ND1 A:HIS1088 4.1 20.9 1.0 CG A:HIS1088 4.3 20.4 1.0 O A:CYS1037 4.3 21.6 1.0 C A:CYS1037 4.3 22.7 1.0 CA A:CYS1040 4.3 18.4 1.0 CA A:GLY1036 4.4 24.3 1.0 N A:GLY1036 4.5 26.7 1.0 CB A:LEU1039 4.5 21.6 1.0 C A:LEU1039 4.7 20.7 1.0 CA A:CYS1034 4.7 27.2 1.0 O A:GLY1036 4.7 26.2 1.0 N A:LEU1039 4.7 22.8 1.0 CB A:SER1090 4.8 23.2 1.0 OG A:SER1090 4.8 21.9 1.0 CA A:LEU1039 4.9 21.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Rubella Protease


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Rubella Protease within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1410 b:27.0 occ:1.00 SG A:CYS1227 2.3 21.7 1.0 SG A:CYS1178 2.3 19.8 1.0 SG A:CYS1225 2.3 19.2 1.0 SG A:CYS1175 2.3 20.9 1.0 CB A:CYS1175 3.2 21.6 1.0 CB A:CYS1225 3.4 20.0 1.0 CB A:CYS1227 3.4 20.4 1.0 CB A:CYS1178 3.5 19.6 1.0 N A:SER1228 3.6 19.2 0.6 N A:SER1228 3.6 19.2 0.4 N A:CYS1178 3.7 19.1 1.0 C A:CYS1227 3.8 19.5 1.0 CA A:CYS1227 3.9 20.2 1.0 N A:CYS1227 4.1 20.4 1.0 O A:HOH1639 4.2 33.1 1.0 CA A:CYS1178 4.2 18.9 1.0 CA A:SER1228 4.3 20.0 0.4 CA A:SER1228 4.3 18.6 0.6 CB A:SER1228 4.4 19.8 0.4 CB A:SER1228 4.4 18.4 0.6 CB A:ARG1177 4.5 19.0 1.0 CB A:SER1172 4.5 26.3 1.0 O A:CYS1227 4.6 19.4 1.0 NE A:ARG1177 4.6 23.5 1.0 CA A:CYS1175 4.7 22.2 1.0 CA A:CYS1225 4.7 20.7 1.0 C A:ARG1177 4.8 18.7 1.0 C A:CYS1225 4.9 20.4 1.0

E.Z.K.Cheong, J.P.Quek, L.Xin, C.Li, J.Y.Chan, C.W.Liew, Y.Mu, J.Zheng, D.Luo. Crystal Structure of the Rubella Virus Protease Reveals A Unique Papain-Like Protease Fold. J.Biol.Chem. V. 298 02250 2022.
ISSN: ESSN 1083-351X
PubMed: 35835220
DOI: 10.1016/J.JBC.2022.102250