Zinc in PDB 6u4n: Solution Structure of Paxillin LIM4 in Complex with Kindlin-2 F0

The binding sites of Zinc atom in the Solution Structure of Paxillin LIM4 in Complex with Kindlin-2 F0 (pdb code 6u4n). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of Paxillin LIM4 in Complex with Kindlin-2 F0, PDB code: 6u4n:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of Paxillin LIM4 in Complex with Kindlin-2 F0


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of Paxillin LIM4 in Complex with Kindlin-2 F0 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn701 b:0.0 occ:1.00 ND1 B:HIS569 2.0 0.0 1.0 ND1 B:HIS572 2.0 0.0 1.0 SG B:CYS552 2.3 0.0 1.0 SG B:CYS549 2.3 0.0 1.0 HB2 B:HIS569 2.7 0.0 1.0 HB2 B:CYS552 2.7 0.0 1.0 CE1 B:HIS572 3.0 0.0 1.0 CE1 B:HIS569 3.0 0.0 1.0 CB B:CYS552 3.0 0.0 1.0 CG B:HIS569 3.0 0.0 1.0 CG B:HIS572 3.1 0.0 1.0 HE1 B:HIS572 3.2 0.0 1.0 HB2 B:HIS572 3.2 0.0 1.0 HE1 B:HIS569 3.2 0.0 1.0 HB3 B:CYS549 3.3 0.0 1.0 H B:HIS569 3.3 0.0 1.0 CB B:HIS569 3.4 0.0 1.0 CB B:CYS549 3.4 0.0 1.0 HB3 B:CYS552 3.5 0.0 1.0 CB B:HIS572 3.5 0.0 1.0 HB3 B:HIS572 3.7 0.0 1.0 HB2 B:CYS549 3.7 0.0 1.0 HB3 B:HIS569 4.1 0.0 1.0 N B:HIS569 4.1 0.0 1.0 NE2 B:HIS572 4.2 0.0 1.0 CD2 B:HIS569 4.2 0.0 1.0 NE2 B:HIS569 4.2 0.0 1.0 CD2 B:HIS572 4.2 0.0 1.0 H B:CYS552 4.3 0.0 1.0 CA B:CYS552 4.3 0.0 1.0 CA B:HIS569 4.4 0.0 1.0 O B:CYS549 4.5 0.0 1.0 N B:CYS552 4.5 0.0 1.0 HD1 B:PHE568 4.7 0.0 1.0 CA B:CYS549 4.7 0.0 1.0 H B:HIS572 4.8 0.0 1.0 HA B:CYS552 4.8 0.0 1.0 HA B:PHE568 4.9 0.0 1.0 C B:CYS549 4.9 0.0 1.0 HA B:HIS569 4.9 0.0 1.0 CA B:HIS572 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of Paxillin LIM4 in Complex with Kindlin-2 F0


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of Paxillin LIM4 in Complex with Kindlin-2 F0 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn702 b:0.0 occ:1.00 SG B:CYS575 2.3 0.0 1.0 SG B:CYS596 2.3 0.0 1.0 SG B:CYS599 2.3 0.0 1.0 SG B:CYS578 2.3 0.0 1.0 HB3 B:PHE577 2.9 0.0 1.0 H B:CYS596 2.9 0.0 1.0 HB3 B:CYS575 3.0 0.0 1.0 HB2 B:CYS596 3.1 0.0 1.0 H B:CYS578 3.1 0.0 1.0 CB B:CYS575 3.2 0.0 1.0 CB B:CYS596 3.3 0.0 1.0 HB2 B:CYS599 3.4 0.0 1.0 CB B:CYS599 3.4 0.0 1.0 HD2 B:PHE577 3.5 0.0 1.0 HB2 B:CYS575 3.5 0.0 1.0 N B:CYS596 3.7 0.0 1.0 HB3 B:CYS599 3.8 0.0 1.0 N B:CYS578 3.9 0.0 1.0 CB B:CYS578 3.9 0.0 1.0 CB B:PHE577 3.9 0.0 1.0 CA B:CYS596 4.1 0.0 1.0 HB3 B:CYS578 4.1 0.0 1.0 HB3 B:CYS596 4.2 0.0 1.0 O B:CYS578 4.2 0.0 1.0 CD2 B:PHE577 4.3 0.0 1.0 HD12 B:LEU582 4.4 0.0 1.0 HB2 B:PHE577 4.4 0.0 1.0 CA B:CYS578 4.4 0.0 1.0 HA B:TYR595 4.4 0.0 1.0 H B:PHE577 4.5 0.0 1.0 CA B:CYS575 4.6 0.0 1.0 HE2 B:LYS580 4.6 0.0 1.0 CG B:PHE577 4.6 0.0 1.0 HD1 B:TYR595 4.6 0.0 1.0 C B:CYS578 4.6 0.0 1.0 HB2 B:CYS578 4.7 0.0 1.0 H B:CYS599 4.7 0.0 1.0 CA B:CYS599 4.8 0.0 1.0 CA B:PHE577 4.8 0.0 1.0 N B:PHE577 4.8 0.0 1.0 C B:PHE577 4.8 0.0 1.0 C B:TYR595 4.8 0.0 1.0 C B:CYS575 4.8 0.0 1.0 O B:GLN581 4.8 0.0 1.0 O B:CYS575 4.9 0.0 1.0 HA B:CYS596 4.9 0.0 1.0 H B:CYS575 4.9 0.0 1.0

L.Zhu, H.Liu, F.Lu, J.Yang, T.V.Byzova, J.Qin. Structural Basis of Paxillin Recruitment By Kindlin-2 in Regulating Cell Adhesion. Structure V. 27 1686 2019.
ISSN: ISSN 0969-2126
PubMed: 31590942
DOI: 10.1016/J.STR.2019.09.006