Zinc in PDB 6fga: Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Enzymatic activity of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
All present enzymatic activity of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1:
2.3.2.23;
2.3.2.24;
2.3.2.27;
Protein crystallography data
The structure of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1, PDB code: 6fga
was solved by
M.Anandapadamanaban,
M.Moche,
M.Sunnerhagen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
47.90 /
2.82
|
Space group
|
C 1 2 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
103.835,
95.871,
235.097,
90.00,
93.15,
90.00
|
R / Rfree (%)
|
25.3 /
29.4
|
Zinc Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
16;
Binding sites:
The binding sites of Zinc atom in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
(pdb code 6fga). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 16 binding sites of Zinc where determined in the
Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1, PDB code: 6fga:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 16 in 6fga
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Zinc Binding Sites List in 6fga
Zinc binding site 1 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn101
b:66.7
occ:1.00
|
SG
|
A:CYS51
|
2.2
|
89.4
|
1.0
|
SG
|
A:CYS31
|
2.2
|
59.2
|
1.0
|
ND1
|
A:HIS33
|
2.3
|
85.7
|
1.0
|
SG
|
A:CYS54
|
2.4
|
83.2
|
1.0
|
CG
|
A:HIS33
|
3.1
|
83.6
|
1.0
|
CB
|
A:CYS51
|
3.1
|
91.8
|
1.0
|
CE1
|
A:HIS33
|
3.2
|
83.4
|
1.0
|
CB
|
A:CYS31
|
3.4
|
63.8
|
1.0
|
CB
|
A:HIS33
|
3.4
|
85.4
|
1.0
|
CB
|
A:CYS54
|
3.6
|
81.8
|
1.0
|
N
|
A:CYS54
|
3.7
|
78.3
|
1.0
|
CD2
|
A:HIS33
|
4.1
|
85.6
|
1.0
|
NE2
|
A:HIS33
|
4.1
|
86.2
|
1.0
|
CA
|
A:CYS54
|
4.2
|
86.4
|
1.0
|
CB
|
A:VAL53
|
4.3
|
96.4
|
1.0
|
CD1
|
A:ILE29
|
4.5
|
0.0
|
1.0
|
N
|
A:HIS33
|
4.5
|
71.7
|
1.0
|
CA
|
A:CYS51
|
4.6
|
80.5
|
1.0
|
CA
|
A:HIS33
|
4.6
|
82.0
|
1.0
|
C
|
A:VAL53
|
4.7
|
87.4
|
1.0
|
CA
|
A:CYS31
|
4.7
|
67.2
|
1.0
|
CA
|
A:VAL53
|
4.8
|
93.8
|
1.0
|
N
|
A:VAL53
|
4.8
|
94.1
|
1.0
|
C
|
A:CYS54
|
4.9
|
92.2
|
1.0
|
N
|
A:ARG55
|
4.9
|
93.4
|
1.0
|
CG1
|
A:VAL53
|
4.9
|
92.3
|
1.0
|
C
|
A:CYS31
|
5.0
|
70.9
|
1.0
|
|
Zinc binding site 2 out
of 16 in 6fga
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Zinc Binding Sites List in 6fga
Zinc binding site 2 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn102
b:0.8
occ:1.00
|
SG
|
A:CYS39
|
2.2
|
0.5
|
1.0
|
SG
|
A:CYS16
|
2.2
|
0.2
|
1.0
|
SG
|
A:CYS36
|
2.6
|
0.5
|
1.0
|
SG
|
A:CYS19
|
2.8
|
0.2
|
1.0
|
CB
|
A:CYS16
|
3.0
|
0.8
|
1.0
|
CB
|
A:CYS36
|
3.0
|
0.7
|
1.0
|
CB
|
A:CYS39
|
3.1
|
0.3
|
1.0
|
CB
|
A:CYS19
|
3.6
|
100.0
|
1.0
|
N
|
A:CYS36
|
3.7
|
1.0
|
1.0
|
N
|
A:CYS19
|
3.8
|
0.4
|
1.0
|
CA
|
A:CYS36
|
4.0
|
0.8
|
1.0
|
CA
|
A:CYS19
|
4.3
|
0.9
|
1.0
|
CA
|
A:CYS16
|
4.4
|
0.4
|
1.0
|
CA
|
A:CYS39
|
4.5
|
0.5
|
1.0
|
CB
|
A:ILE18
|
4.5
|
0.5
|
1.0
|
C
|
A:ILE18
|
4.7
|
0.3
|
1.0
|
N
|
A:CYS39
|
4.8
|
0.7
|
1.0
|
C
|
A:CYS16
|
4.8
|
0.2
|
1.0
|
N
|
A:ILE18
|
4.9
|
0.9
|
1.0
|
C
|
A:CYS36
|
4.9
|
0.3
|
1.0
|
C
|
A:PHE35
|
4.9
|
0.4
|
1.0
|
O
|
A:CYS36
|
4.9
|
0.8
|
1.0
|
CA
|
A:ILE18
|
4.9
|
0.1
|
1.0
|
O
|
A:CYS16
|
4.9
|
0.7
|
1.0
|
|
Zinc binding site 3 out
of 16 in 6fga
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Zinc Binding Sites List in 6fga
Zinc binding site 3 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn101
b:93.2
occ:1.00
|
SG
|
B:CYS54
|
2.2
|
0.9
|
1.0
|
SG
|
B:CYS51
|
2.2
|
99.6
|
1.0
|
SG
|
B:CYS31
|
2.3
|
79.0
|
1.0
|
ND1
|
B:HIS33
|
2.3
|
87.5
|
1.0
|
CB
|
B:CYS51
|
3.1
|
0.2
|
1.0
|
CB
|
B:CYS31
|
3.2
|
97.8
|
1.0
|
CE1
|
B:HIS33
|
3.2
|
86.7
|
1.0
|
CG
|
B:HIS33
|
3.2
|
85.7
|
1.0
|
CB
|
B:CYS54
|
3.5
|
0.7
|
1.0
|
CB
|
B:HIS33
|
3.5
|
92.2
|
1.0
|
N
|
B:CYS54
|
3.7
|
97.3
|
1.0
|
CA
|
B:CYS54
|
4.1
|
99.5
|
1.0
|
NE2
|
B:HIS33
|
4.2
|
81.8
|
1.0
|
CD2
|
B:HIS33
|
4.3
|
84.5
|
1.0
|
CB
|
B:VAL53
|
4.4
|
0.7
|
1.0
|
N
|
B:HIS33
|
4.5
|
1.0
|
1.0
|
CA
|
B:CYS31
|
4.5
|
0.3
|
1.0
|
CA
|
B:CYS51
|
4.6
|
96.8
|
1.0
|
N
|
B:ARG55
|
4.6
|
99.6
|
1.0
|
CD1
|
B:ILE29
|
4.7
|
99.9
|
1.0
|
CA
|
B:HIS33
|
4.7
|
0.1
|
1.0
|
C
|
B:CYS54
|
4.7
|
96.5
|
1.0
|
C
|
B:VAL53
|
4.7
|
97.5
|
1.0
|
C
|
B:CYS31
|
4.7
|
0.2
|
1.0
|
N
|
B:VAL53
|
4.8
|
86.1
|
1.0
|
CA
|
B:VAL53
|
4.9
|
99.0
|
1.0
|
N
|
B:GLN56
|
4.9
|
97.2
|
1.0
|
O
|
B:CYS31
|
5.0
|
0.8
|
1.0
|
|
Zinc binding site 4 out
of 16 in 6fga
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Zinc Binding Sites List in 6fga
Zinc binding site 4 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn102
b:89.7
occ:1.00
|
SG
|
B:CYS19
|
2.3
|
90.0
|
1.0
|
SG
|
B:CYS16
|
2.3
|
92.2
|
1.0
|
SG
|
B:CYS39
|
2.5
|
96.4
|
1.0
|
SG
|
B:CYS36
|
2.7
|
0.3
|
1.0
|
CB
|
B:CYS16
|
2.8
|
96.5
|
1.0
|
CB
|
B:CYS19
|
3.3
|
90.5
|
1.0
|
CB
|
B:CYS36
|
3.4
|
94.2
|
1.0
|
CB
|
B:CYS39
|
3.5
|
0.2
|
1.0
|
N
|
B:CYS19
|
3.6
|
0.7
|
1.0
|
CA
|
B:CYS19
|
4.0
|
99.6
|
1.0
|
N
|
B:CYS36
|
4.1
|
93.0
|
1.0
|
CA
|
B:CYS16
|
4.3
|
0.0
|
1.0
|
CA
|
B:CYS36
|
4.4
|
95.8
|
1.0
|
CB
|
B:ILE18
|
4.6
|
97.7
|
1.0
|
C
|
B:ILE18
|
4.6
|
0.0
|
1.0
|
C
|
B:CYS16
|
4.7
|
0.5
|
1.0
|
O
|
B:CYS16
|
4.7
|
99.6
|
1.0
|
O
|
B:ASP21
|
4.8
|
0.8
|
1.0
|
C
|
B:CYS19
|
4.9
|
0.3
|
1.0
|
CA
|
B:CYS39
|
4.9
|
0.7
|
1.0
|
N
|
B:ILE18
|
4.9
|
91.3
|
1.0
|
N
|
B:LEU20
|
4.9
|
0.1
|
1.0
|
CA
|
B:ILE18
|
4.9
|
96.9
|
1.0
|
|
Zinc binding site 5 out
of 16 in 6fga
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Zinc Binding Sites List in 6fga
Zinc binding site 5 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn101
b:80.0
occ:1.00
|
ND1
|
C:HIS33
|
2.0
|
0.1
|
1.0
|
SG
|
C:CYS54
|
2.3
|
77.2
|
1.0
|
SG
|
C:CYS31
|
2.4
|
1.0
|
1.0
|
SG
|
C:CYS51
|
2.5
|
87.5
|
1.0
|
CE1
|
C:HIS33
|
2.8
|
0.1
|
1.0
|
CG
|
C:HIS33
|
2.9
|
0.4
|
1.0
|
CB
|
C:CYS31
|
3.3
|
0.1
|
1.0
|
CB
|
C:HIS33
|
3.3
|
0.4
|
1.0
|
CB
|
C:CYS51
|
3.4
|
82.5
|
1.0
|
CB
|
C:CYS54
|
3.5
|
82.7
|
1.0
|
N
|
C:CYS54
|
3.7
|
80.0
|
1.0
|
NE2
|
C:HIS33
|
3.9
|
0.3
|
1.0
|
CD2
|
C:HIS33
|
3.9
|
0.9
|
1.0
|
CA
|
C:CYS54
|
4.2
|
81.0
|
1.0
|
CB
|
C:VAL53
|
4.2
|
76.9
|
1.0
|
N
|
C:HIS33
|
4.4
|
0.5
|
1.0
|
CA
|
C:HIS33
|
4.5
|
0.9
|
1.0
|
CA
|
C:CYS31
|
4.7
|
98.9
|
1.0
|
C
|
C:VAL53
|
4.7
|
78.0
|
1.0
|
CG1
|
C:VAL53
|
4.8
|
75.8
|
1.0
|
CD1
|
C:ILE29
|
4.8
|
99.4
|
1.0
|
CA
|
C:VAL53
|
4.8
|
79.6
|
1.0
|
C
|
C:CYS31
|
4.9
|
93.6
|
1.0
|
CA
|
C:CYS51
|
4.9
|
82.9
|
1.0
|
N
|
C:VAL53
|
4.9
|
82.1
|
1.0
|
C
|
C:CYS54
|
4.9
|
78.9
|
1.0
|
|
Zinc binding site 6 out
of 16 in 6fga
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Zinc Binding Sites List in 6fga
Zinc binding site 6 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn102
b:87.7
occ:1.00
|
SG
|
C:CYS19
|
2.2
|
79.2
|
1.0
|
SG
|
C:CYS39
|
2.5
|
90.3
|
1.0
|
SG
|
C:CYS36
|
2.5
|
0.1
|
1.0
|
SG
|
C:CYS16
|
2.7
|
79.2
|
1.0
|
CB
|
C:CYS16
|
3.0
|
84.3
|
1.0
|
CB
|
C:CYS19
|
3.2
|
86.1
|
1.0
|
CB
|
C:CYS36
|
3.2
|
0.5
|
1.0
|
CB
|
C:CYS39
|
3.7
|
95.2
|
1.0
|
N
|
C:CYS19
|
3.8
|
84.2
|
1.0
|
CA
|
C:CYS19
|
4.1
|
85.4
|
1.0
|
N
|
C:CYS36
|
4.2
|
97.3
|
1.0
|
CA
|
C:CYS36
|
4.3
|
0.6
|
1.0
|
CA
|
C:CYS16
|
4.5
|
85.2
|
1.0
|
O
|
C:ASP21
|
4.8
|
0.8
|
1.0
|
C
|
C:ILE18
|
4.9
|
94.5
|
1.0
|
C
|
C:CYS19
|
4.9
|
89.8
|
1.0
|
|
Zinc binding site 7 out
of 16 in 6fga
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Zinc Binding Sites List in 6fga
Zinc binding site 7 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn101
b:51.6
occ:1.00
|
ND1
|
D:HIS33
|
2.1
|
68.1
|
1.0
|
SG
|
D:CYS54
|
2.2
|
54.1
|
1.0
|
SG
|
D:CYS31
|
2.3
|
57.1
|
1.0
|
SG
|
D:CYS51
|
2.4
|
58.1
|
1.0
|
CE1
|
D:HIS33
|
3.0
|
69.2
|
1.0
|
CB
|
D:CYS51
|
3.1
|
68.2
|
1.0
|
CG
|
D:HIS33
|
3.2
|
69.4
|
1.0
|
CB
|
D:CYS31
|
3.3
|
60.4
|
1.0
|
CB
|
D:HIS33
|
3.6
|
77.1
|
1.0
|
CB
|
D:CYS54
|
3.6
|
56.1
|
1.0
|
N
|
D:CYS54
|
3.7
|
54.2
|
1.0
|
NE2
|
D:HIS33
|
4.1
|
73.8
|
1.0
|
CA
|
D:CYS54
|
4.2
|
58.1
|
1.0
|
CD2
|
D:HIS33
|
4.2
|
72.3
|
1.0
|
CB
|
D:VAL53
|
4.5
|
49.1
|
1.0
|
CD1
|
D:ILE29
|
4.6
|
71.7
|
1.0
|
CA
|
D:CYS51
|
4.6
|
61.9
|
1.0
|
N
|
D:HIS33
|
4.6
|
69.5
|
1.0
|
CA
|
D:CYS31
|
4.6
|
66.6
|
1.0
|
CA
|
D:HIS33
|
4.7
|
73.9
|
1.0
|
C
|
D:CYS54
|
4.7
|
61.8
|
1.0
|
C
|
D:VAL53
|
4.7
|
52.9
|
1.0
|
N
|
D:ARG55
|
4.7
|
66.2
|
1.0
|
CB
|
D:GLN56
|
4.8
|
83.6
|
1.0
|
C
|
D:CYS31
|
4.8
|
69.6
|
1.0
|
N
|
D:GLN56
|
4.9
|
87.0
|
1.0
|
N
|
D:VAL53
|
5.0
|
51.3
|
1.0
|
CA
|
D:VAL53
|
5.0
|
50.6
|
1.0
|
|
Zinc binding site 8 out
of 16 in 6fga
Go back to
Zinc Binding Sites List in 6fga
Zinc binding site 8 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn102
b:85.8
occ:1.00
|
SG
|
D:CYS39
|
2.3
|
98.3
|
1.0
|
SG
|
D:CYS16
|
2.3
|
64.4
|
1.0
|
SG
|
D:CYS19
|
2.6
|
93.1
|
1.0
|
SG
|
D:CYS36
|
2.7
|
97.2
|
1.0
|
CB
|
D:CYS16
|
3.0
|
66.1
|
1.0
|
CB
|
D:CYS36
|
3.1
|
88.1
|
1.0
|
CB
|
D:CYS39
|
3.3
|
96.6
|
1.0
|
CB
|
D:CYS19
|
3.5
|
0.2
|
1.0
|
N
|
D:CYS19
|
3.9
|
0.7
|
1.0
|
N
|
D:CYS36
|
3.9
|
81.9
|
1.0
|
CA
|
D:CYS36
|
4.1
|
91.6
|
1.0
|
CA
|
D:CYS19
|
4.3
|
0.9
|
1.0
|
CA
|
D:CYS16
|
4.4
|
71.5
|
1.0
|
CA
|
D:CYS39
|
4.6
|
99.3
|
1.0
|
CB
|
D:ILE18
|
4.7
|
87.3
|
1.0
|
C
|
D:ILE18
|
4.8
|
0.3
|
1.0
|
N
|
D:CYS39
|
4.9
|
0.9
|
1.0
|
C
|
D:CYS16
|
4.9
|
78.3
|
1.0
|
|
Zinc binding site 9 out
of 16 in 6fga
Go back to
Zinc Binding Sites List in 6fga
Zinc binding site 9 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn101
b:46.4
occ:1.00
|
SG
|
E:CYS51
|
2.2
|
51.0
|
1.0
|
ND1
|
E:HIS33
|
2.2
|
66.1
|
1.0
|
SG
|
E:CYS54
|
2.2
|
63.9
|
1.0
|
SG
|
E:CYS31
|
2.5
|
89.3
|
1.0
|
CG
|
E:HIS33
|
3.0
|
74.0
|
1.0
|
CE1
|
E:HIS33
|
3.1
|
72.7
|
1.0
|
CB
|
E:CYS51
|
3.3
|
43.8
|
1.0
|
CB
|
E:HIS33
|
3.4
|
76.2
|
1.0
|
CB
|
E:CYS31
|
3.5
|
79.8
|
1.0
|
CB
|
E:CYS54
|
3.5
|
61.5
|
1.0
|
N
|
E:CYS54
|
3.6
|
55.7
|
1.0
|
CD2
|
E:HIS33
|
4.1
|
73.0
|
1.0
|
NE2
|
E:HIS33
|
4.1
|
74.0
|
1.0
|
CA
|
E:CYS54
|
4.1
|
57.6
|
1.0
|
CB
|
E:VAL53
|
4.1
|
46.4
|
1.0
|
C
|
E:VAL53
|
4.5
|
51.5
|
1.0
|
N
|
E:HIS33
|
4.6
|
76.2
|
1.0
|
CA
|
E:HIS33
|
4.6
|
76.0
|
1.0
|
CA
|
E:CYS51
|
4.7
|
48.0
|
1.0
|
CA
|
E:VAL53
|
4.7
|
45.3
|
1.0
|
CG1
|
E:VAL53
|
4.7
|
48.3
|
1.0
|
CD1
|
E:ILE29
|
4.7
|
56.0
|
1.0
|
N
|
E:VAL53
|
4.7
|
43.3
|
1.0
|
CA
|
E:CYS31
|
4.8
|
75.5
|
1.0
|
C
|
E:CYS54
|
4.8
|
49.8
|
1.0
|
N
|
E:ARG55
|
4.9
|
51.5
|
1.0
|
CB
|
E:GLN56
|
5.0
|
62.9
|
1.0
|
|
Zinc binding site 10 out
of 16 in 6fga
Go back to
Zinc Binding Sites List in 6fga
Zinc binding site 10 out
of 16 in the Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of Crystal Structure of TRIM21 E3 Ligase, Ring Domain in Complex with Its Cognate E2 Conjugating Enzyme UBE2E1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn102
b:49.3
occ:1.00
|
SG
|
E:CYS16
|
2.2
|
51.1
|
1.0
|
SG
|
E:CYS39
|
2.2
|
45.8
|
1.0
|
SG
|
E:CYS36
|
2.6
|
61.0
|
1.0
|
SG
|
E:CYS19
|
2.7
|
57.3
|
1.0
|
CB
|
E:CYS16
|
3.1
|
47.5
|
1.0
|
CB
|
E:CYS36
|
3.1
|
68.7
|
1.0
|
CB
|
E:CYS39
|
3.1
|
62.8
|
1.0
|
CB
|
E:CYS19
|
3.4
|
52.2
|
1.0
|
N
|
E:CYS19
|
3.8
|
54.6
|
1.0
|
N
|
E:CYS36
|
3.8
|
55.1
|
1.0
|
CA
|
E:CYS36
|
4.1
|
59.8
|
1.0
|
CA
|
E:CYS19
|
4.3
|
56.5
|
1.0
|
CA
|
E:CYS16
|
4.5
|
50.1
|
1.0
|
CA
|
E:CYS39
|
4.5
|
62.7
|
1.0
|
CB
|
E:ILE18
|
4.6
|
58.6
|
1.0
|
O
|
E:CYS36
|
4.7
|
54.6
|
1.0
|
C
|
E:ILE18
|
4.8
|
55.4
|
1.0
|
N
|
E:CYS39
|
4.8
|
55.3
|
1.0
|
C
|
E:CYS16
|
4.9
|
53.9
|
1.0
|
C
|
E:CYS36
|
4.9
|
59.4
|
1.0
|
N
|
E:ILE18
|
5.0
|
50.8
|
1.0
|
O
|
E:CYS16
|
5.0
|
59.6
|
1.0
|
|
Reference:
M.Anandapadamanaban,
N.C.Kyriakidis,
V.Csizmok,
A.Wallenhammar,
A.C.Espinosa,
A.Ahlner,
A.R.Round,
J.Trewhella,
M.Moche,
M.Wahren-Herlenius,
M.Sunnerhagen.
E3 Ubiquitin-Protein Ligase TRIM21-Mediated Lysine Capture By UBE2E1 Reveals Substrate-Targeting Mode of A Ubiquitin-Conjugating E2. J.Biol.Chem. V. 294 11404 2019.
ISSN: ESSN 1083-351X
PubMed: 31160341
DOI: 10.1074/JBC.RA119.008485
Page generated: Mon Oct 28 20:59:24 2024
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