Zinc in PDB 6cta: Structure of the Human Cgas-Dna Complex with Atp

All present enzymatic activity of Structure of the Human Cgas-Dna Complex with Atp:
2.7.7.86;

The structure of Structure of the Human Cgas-Dna Complex with Atp, PDB code: 6cta was solved by W.Zhou, A.T.Whiteley, C.C.De Oliveira Mann, B.R.Morehouse, J.J.Mekalanos, P.J.Kranzusch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.83 / 2.78
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	99.782, 99.782, 236.769, 90.00, 90.00, 120.00
R / Rfree (%)	21.1 / 24.6

The structure of Structure of the Human Cgas-Dna Complex with Atp also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Zinc atom in the Structure of the Human Cgas-Dna Complex with Atp (pdb code 6cta). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of the Human Cgas-Dna Complex with Atp, PDB code: 6cta:

Zinc binding site 1 out of 1 in the Structure of the Human Cgas-Dna Complex with Atp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Human Cgas-Dna Complex with Atp within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn601 b:53.2 occ:1.00 NE2 A:HIS390 2.1 53.4 1.0 SG A:CYS397 2.3 53.5 1.0 SG A:CYS404 2.4 52.8 1.0 SG A:CYS396 2.4 44.4 1.0 CD2 A:HIS390 2.8 47.6 1.0 CE1 A:HIS390 3.2 48.0 1.0 CB A:CYS404 3.3 45.6 1.0 CB A:CYS397 3.4 48.3 1.0 CB A:CYS396 3.7 39.2 1.0 N A:CYS397 3.7 51.1 1.0 N A:CYS404 3.8 52.5 1.0 C A:CYS396 3.9 48.9 1.0 CG A:HIS390 4.1 47.8 1.0 CA A:CYS404 4.1 47.8 1.0 CA A:CYS397 4.1 51.4 1.0 NH2 A:ARG406 4.1 43.4 1.0 ND1 A:HIS390 4.2 48.1 1.0 O A:CYS396 4.3 51.8 1.0 CA A:CYS396 4.3 42.6 1.0 O A:GLU402 4.4 62.8 1.0 C A:CYS404 4.6 53.2 1.0 O A:CYS404 4.7 51.8 1.0

W.Zhou, A.T.Whiteley, C.C.De Oliveira Mann, B.R.Morehouse, R.P.Nowak, E.S.Fischer, N.S.Gray, J.J.Mekalanos, P.J.Kranzusch. Structure of the Human Cgas-Dna Complex Reveals Enhanced Control of Immune Surveillance. Cell V. 174 300 2018.
ISSN: ISSN 1097-4172
PubMed: 30007416
DOI: 10.1016/J.CELL.2018.06.026