Zinc in PDB 6c04: Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp

All present enzymatic activity of Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp:
2.7.7.6;

The structure of Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp (pdb code 6c04). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp, PDB code: 6c04:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn2000 b:87.2 occ:1.00 SG D:CYS978 2.4 56.4 1.0 SG D:CYS968 2.5 61.8 1.0 SG D:CYS975 2.5 58.4 1.0 SG D:CYS891 2.5 65.6 1.0 CB D:CYS975 2.6 58.4 1.0 CB D:CYS978 2.9 56.4 1.0 CB D:CYS891 3.6 65.6 1.0 CA D:CYS975 3.6 58.4 1.0 N D:CYS975 3.7 58.4 1.0 CB D:CYS968 3.8 61.8 1.0 N D:CYS978 4.0 56.4 1.0 N D:CYS891 4.0 65.6 1.0 CA D:CYS978 4.0 56.4 1.0 CA D:CYS968 4.2 61.8 1.0 CG2 D:THR970 4.3 63.5 1.0 C D:CYS975 4.3 58.4 1.0 N D:ALA969 4.4 65.5 1.0 CA D:CYS891 4.4 65.6 1.0 O D:CYS975 4.5 58.4 1.0 C D:VAL974 4.8 53.2 1.0 C D:CYS968 4.8 61.8 1.0 CG2 D:THR893 5.0 70.0 1.0

Zinc binding site 2 out of 2 in the Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mtb Rnap Holo/Rbpa/Double Fork Dna -Closed Clamp within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn2001 b:96.7 occ:1.00 SG D:CYS78 2.4 78.6 1.0 SG D:CYS60 2.4 81.3 1.0 SG D:CYS75 2.5 79.6 1.0 SG D:CYS62 2.5 83.2 1.0 CB D:CYS78 3.0 78.6 1.0 N D:CYS62 3.0 83.2 1.0 CB D:CYS62 3.1 83.2 1.0 CB D:CYS75 3.4 79.6 1.0 CB D:CYS60 3.4 81.3 1.0 CA D:CYS62 3.6 83.2 1.0 N D:TYR61 3.7 78.2 1.0 N D:GLY63 3.9 83.0 1.0 N D:CYS78 4.0 78.6 1.0 CA D:CYS78 4.1 78.6 1.0 C D:TYR61 4.1 78.2 1.0 C D:CYS62 4.2 83.2 1.0 CA D:TYR61 4.4 78.2 1.0 C D:CYS60 4.4 81.3 1.0 N D:LYS64 4.5 82.3 1.0 CA D:CYS60 4.5 81.3 1.0 CB D:TYR61 4.7 78.2 1.0 C D:ARG77 4.8 84.9 1.0 CA D:CYS75 4.8 79.6 1.0 C D:CYS78 4.9 78.6 1.0 CB D:LYS64 4.9 82.3 1.0

H.Boyaci, J.Chen, M.Lilic, M.Palka, R.A.Mooney, R.Landick, S.A.Darst, E.A.Campbell. Fidaxomicin Jamsmycobacterium Tuberculosisrna Polymerase Motions Needed For Initiation Via Rbpa Contacts. Elife V. 7 2018.
ISSN: ESSN 2050-084X
PubMed: 29480804
DOI: 10.7554/ELIFE.34823