Zinc in PDB 5yn8: Crystal Structure of Mers-Cov NSP16/NSP10 Complex Bound to Sah

The structure of Crystal Structure of Mers-Cov NSP16/NSP10 Complex Bound to Sah, PDB code: 5yn8 was solved by S.M.Wei, L.Yang, Z.H.Ke, Y.Chen, D.Y.Guo, C.P.Fan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.25 / 1.97
Space group	P 21 2 21
Cell size a, b, c (Å), α, β, γ (°)	66.399, 70.233, 119.203, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 22.2

The binding sites of Zinc atom in the Crystal Structure of Mers-Cov NSP16/NSP10 Complex Bound to Sah (pdb code 5yn8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mers-Cov NSP16/NSP10 Complex Bound to Sah, PDB code: 5yn8:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Mers-Cov NSP16/NSP10 Complex Bound to Sah


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mers-Cov NSP16/NSP10 Complex Bound to Sah within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:46.3 occ:1.00 NE2 B:HIS83 1.8 53.5 1.0 CE1 B:HIS83 2.0 49.9 1.0 SG B:CYS90 2.3 52.6 1.0 SG B:CYS77 2.3 41.3 1.0 SG B:CYS74 2.3 45.7 1.0 CB B:CYS90 3.1 49.1 1.0 CB B:CYS74 3.2 45.9 1.0 CD2 B:HIS83 3.2 54.1 1.0 ND1 B:HIS83 3.3 52.2 1.0 CB B:CYS77 3.3 42.5 1.0 N B:CYS77 3.5 45.4 1.0 CA B:CYS77 3.9 45.0 1.0 CG B:HIS83 3.9 50.9 1.0 CA B:CYS90 4.2 52.8 1.0 C B:TYR76 4.5 48.0 1.0 CB B:TYR76 4.5 48.4 1.0 CA B:CYS74 4.6 46.0 1.0 CB B:LYS93 4.6 44.1 1.0 O B:HOH317 4.7 48.4 1.0 CA B:TYR76 4.9 50.1 1.0 C B:CYS74 5.0 45.2 1.0 N B:LYS93 5.0 41.7 1.0 O B:CYS74 5.0 44.2 1.0 N B:TYR76 5.0 50.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Mers-Cov NSP16/NSP10 Complex Bound to Sah


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Mers-Cov NSP16/NSP10 Complex Bound to Sah within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn202 b:0.1 occ:1.00 SG B:CYS128 2.2 1.0 1.0 SG B:CYS117 2.3 86.3 1.0 CB B:CYS120 2.4 80.6 1.0 CB B:CYS128 2.5 0.7 1.0 CA B:CYS128 2.5 0.7 1.0 SG B:CYS120 2.6 82.3 1.0 CB B:CYS117 3.2 84.5 1.0 N B:CYS128 3.3 0.5 1.0 C B:CYS128 3.7 0.9 1.0 CA B:CYS120 3.8 80.2 1.0 O B:CYS128 4.1 0.0 1.0 N B:CYS120 4.1 81.6 1.0 C B:GLY127 4.3 0.1 1.0 C B:CYS120 4.6 83.6 1.0 CG1 B:VAL119 4.6 91.7 1.0 CA B:CYS117 4.7 82.3 1.0 O B:GLY127 4.9 0.0 1.0

S.M.Wei, L.Yang, Z.H.Ke, Q.Y.Liu, Z.Z.Yang, Y.Chen, D.Y.Guo, C.P.Fan. Structural Insights Into the Molecular Mechanism of Mers Coronavirus Rna Ribose 2'-O-Methylation By NSP16/NSP10 Protein Complex To Be Published.