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Atomistry » Zinc » PDB 5v37-5vdu » 5v8p | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5v37-5vdu » 5v8p » |
Zinc in PDB 5v8p: Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light ChainEnzymatic activity of Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
All present enzymatic activity of Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain:
3.4.24.69; Protein crystallography data
The structure of Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain, PDB code: 5v8p
was solved by
K.N.Allen,
N.R.Silvaggi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5v8p:
The structure of Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
(pdb code 5v8p). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain, PDB code: 5v8p: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 5v8pGo back to Zinc Binding Sites List in 5v8p
Zinc binding site 1 out
of 2 in the Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 5v8pGo back to Zinc Binding Sites List in 5v8p
Zinc binding site 2 out
of 2 in the Small Molecule Inhibitor Abs-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
Mono view Stereo pair view
Reference:
A.R.Jacobson,
M.Adler,
N.R.Silvaggi,
K.N.Allen,
G.M.Smith,
R.A.Fredenburg,
R.L.Stein,
J.B.Park,
X.Feng,
C.B.Shoemaker,
S.S.Deshpande,
M.C.Goodnough,
C.J.Malizio,
E.A.Johnson,
S.Pellett,
W.H.Tepp,
S.Tzipori.
Small Molecule Metalloprotease Inhibitor with in Vitro, Ex Vivo and in Vivo Efficacy Against Botulinum Neurotoxin Serotype A. Toxicon V. 137 36 2017.
Page generated: Mon Oct 28 12:38:26 2024
ISSN: ISSN 1879-3150 PubMed: 28698055 DOI: 10.1016/J.TOXICON.2017.06.016 |
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