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Zinc in PDB 5v3h: Crystal Structure of SMYD2 with Sam and EPZ033294Enzymatic activity of Crystal Structure of SMYD2 with Sam and EPZ033294
All present enzymatic activity of Crystal Structure of SMYD2 with Sam and EPZ033294:
2.1.1.43; Protein crystallography data
The structure of Crystal Structure of SMYD2 with Sam and EPZ033294, PDB code: 5v3h
was solved by
P.A.Boriack-Sjodin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5v3h:
The structure of Crystal Structure of SMYD2 with Sam and EPZ033294 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of SMYD2 with Sam and EPZ033294
(pdb code 5v3h). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of SMYD2 with Sam and EPZ033294, PDB code: 5v3h: Jump to Zinc binding site number: 1; 2; 3; Zinc binding site 1 out of 3 in 5v3hGo back to Zinc Binding Sites List in 5v3h
Zinc binding site 1 out
of 3 in the Crystal Structure of SMYD2 with Sam and EPZ033294
Mono view Stereo pair view
Zinc binding site 2 out of 3 in 5v3hGo back to Zinc Binding Sites List in 5v3h
Zinc binding site 2 out
of 3 in the Crystal Structure of SMYD2 with Sam and EPZ033294
Mono view Stereo pair view
Zinc binding site 3 out of 3 in 5v3hGo back to Zinc Binding Sites List in 5v3h
Zinc binding site 3 out
of 3 in the Crystal Structure of SMYD2 with Sam and EPZ033294
Mono view Stereo pair view
Reference:
M.J.Thomenius,
J.Totman,
D.Harvey,
L.H.Mitchell,
T.V.Riera,
K.Cosmopoulos,
A.R.Grassian,
C.Klaus,
M.Foley,
E.A.Admirand,
H.Jahic,
C.Majer,
T.Wigle,
S.L.Jacques,
J.Gureasko,
D.Brach,
T.Lingaraj,
K.West,
S.Smith,
N.Rioux,
N.J.Waters,
C.Tang,
A.Raimondi,
M.Munchhof,
J.E.Mills,
S.Ribich,
M.Porter Scott,
K.W.Kuntz,
W.P.Janzen,
M.Moyer,
J.J.Smith,
R.Chesworth,
R.A.Copeland,
P.A.Boriack-Sjodin.
Small Molecule Inhibitors and Crispr/CAS9 Mutagenesis Demonstrate That SMYD2 and SMYD3 Activity Are Dispensable For Autonomous Cancer Cell Proliferation. Plos One V. 13 97372 2018.
Page generated: Wed Dec 16 11:07:34 2020
ISSN: ESSN 1932-6203 PubMed: 29856759 DOI: 10.1371/JOURNAL.PONE.0197372 |
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