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Zinc in PDB 5uhg: Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin
Enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin
All present enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin:
2.7.7.6;
2.7.7.6;
Protein crystallography data
The structure of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin, PDB code: 5uhg
was solved by
W.Lin,
K.Das,
Y.Feng,
R.H.Ebright,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 49.24 / 3.97 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 151.434, 162.147, 194.316, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 22.3 / 26 |
Other elements in 5uhg:
The structure of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin also contains other interesting chemical elements:
| Magnesium | (Mg) | 1 atom |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin
(pdb code 5uhg). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin, PDB code: 5uhg:
Jump to Zinc binding site number: 1; 2;
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin, PDB code: 5uhg:
Jump to Zinc binding site number: 1; 2;
Zinc binding site 1 out of 2 in 5uhg
Go back to
Zinc Binding Sites List in 5uhg
Zinc binding site 1 out
of 2 in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin within 5.0Å range:
|
Zinc binding site 2 out of 2 in 5uhg
Go back to
Zinc Binding Sites List in 5uhg
Zinc binding site 2 out
of 2 in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex in Complex with D-AAP1 and Rifampin within 5.0Å range:
|
Reference:
W.Lin,
S.Mandal,
D.Degen,
Y.Liu,
Y.W.Ebright,
S.Li,
Y.Feng,
Y.Zhang,
S.Mandal,
Y.Jiang,
S.Liu,
M.Gigliotti,
M.Talaue,
N.Connell,
K.Das,
E.Arnold,
R.H.Ebright.
Structural Basis of Mycobacterium Tuberculosis Transcription and Transcription Inhibition. Mol. Cell V. 66 169 2017.
ISSN: ISSN 1097-4164
PubMed: 28392175
DOI: 10.1016/J.MOLCEL.2017.03.001
Page generated: Mon Oct 28 09:35:17 2024
ISSN: ISSN 1097-4164
PubMed: 28392175
DOI: 10.1016/J.MOLCEL.2017.03.001
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