Zinc in PDB 5u6z: Crystal Structure of Xenopus Laevis APEX2 C-Terminal Znf-Grf Domain

All present enzymatic activity of Crystal Structure of Xenopus Laevis APEX2 C-Terminal Znf-Grf Domain:
4.2.99.18;

The structure of Crystal Structure of Xenopus Laevis APEX2 C-Terminal Znf-Grf Domain, PDB code: 5u6z was solved by B.D.Wallace, R.S.Williams, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.17 / 2.60
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	90.332, 90.332, 23.105, 90.00, 90.00, 90.00
R / Rfree (%)	19.5 / 24.5

The binding sites of Zinc atom in the Crystal Structure of Xenopus Laevis APEX2 C-Terminal Znf-Grf Domain (pdb code 5u6z). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Xenopus Laevis APEX2 C-Terminal Znf-Grf Domain, PDB code: 5u6z:

Zinc binding site 1 out of 1 in the Crystal Structure of Xenopus Laevis APEX2 C-Terminal Znf-Grf Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Xenopus Laevis APEX2 C-Terminal Znf-Grf Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn101 b:48.5 occ:1.00 ND1 A:HIS24 2.0 34.1 1.0 SG A:CYS47 2.3 36.7 1.0 SG A:CYS61 2.4 40.2 1.0 SG A:CYS21 2.4 33.3 1.0 CE1 A:HIS24 2.7 34.6 1.0 CB A:CYS47 3.1 33.8 1.0 CG A:HIS24 3.3 33.5 1.0 CB A:CYS21 3.3 35.0 1.0 CB A:CYS61 3.5 31.0 1.0 CB A:HIS24 3.8 31.9 1.0 N A:CYS61 3.9 32.8 1.0 N A:HIS24 3.9 35.9 1.0 NE2 A:HIS24 3.9 32.8 1.0 O A:HOH208 4.1 34.6 1.0 CA A:CYS47 4.2 36.8 1.0 CD2 A:HIS24 4.2 33.5 1.0 CA A:CYS61 4.3 29.0 1.0 C A:GLY23 4.5 36.0 1.0 N A:GLY23 4.5 39.5 1.0 CA A:GLY23 4.5 32.6 1.0 CG A:ARG49 4.5 37.0 1.0 CA A:HIS24 4.5 35.4 1.0 CA A:CYS21 4.7 37.8 1.0 C A:ARG60 4.9 35.9 1.0 C A:CYS61 5.0 30.8 1.0 C A:CYS21 5.0 37.5 1.0 C A:CYS47 5.0 34.6 1.0

B.D.Wallace, Z.Berman, G.A.Mueller, Y.Lin, T.Chang, S.N.Andres, J.L.Wojtaszek, E.F.Derose, C.D.Appel, R.E.London, S.Yan, R.S.Williams. APE2 Zf-Grf Facilitates 3'-5' Resection of Dna Damage Following Oxidative Stress. Proc. Natl. Acad. Sci. V. 114 304 2017U.S.A..
ISSN: ESSN 1091-6490
PubMed: 28028224
DOI: 10.1073/PNAS.1610011114