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Zinc in PDB 5sz5: Carbonic Anhydrase IX-Mimic in Complex with 4-(2-Methylphenyl)- BenzenesulfonamideEnzymatic activity of Carbonic Anhydrase IX-Mimic in Complex with 4-(2-Methylphenyl)- Benzenesulfonamide
All present enzymatic activity of Carbonic Anhydrase IX-Mimic in Complex with 4-(2-Methylphenyl)- Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase IX-Mimic in Complex with 4-(2-Methylphenyl)- Benzenesulfonamide, PDB code: 5sz5
was solved by
A.Bhatt,
B.P.Mahon,
B.Cornelio,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase IX-Mimic in Complex with 4-(2-Methylphenyl)- Benzenesulfonamide
(pdb code 5sz5). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase IX-Mimic in Complex with 4-(2-Methylphenyl)- Benzenesulfonamide, PDB code: 5sz5: Zinc binding site 1 out of 1 in 5sz5Go back to Zinc Binding Sites List in 5sz5
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase IX-Mimic in Complex with 4-(2-Methylphenyl)- Benzenesulfonamide
Mono view Stereo pair view
Reference:
A.Bhatt,
B.P.Mahon,
V.W.Cruzeiro,
B.Cornelio,
M.Laronze-Cochard,
M.Ceruso,
J.Sapi,
G.A.Rance,
A.N.Khlobystov,
A.Fontana,
A.Roitberg,
C.T.Supuran,
R.Mckenna.
Structure-Activity Relationships of Benzenesulfonamide-Based Inhibitors Towards Carbonic Anhydrase Isoform Specificity. Chembiochem V. 18 213 2017.
Page generated: Wed Dec 16 10:53:38 2020
ISSN: ESSN 1439-7633 PubMed: 27860128 DOI: 10.1002/CBIC.201600513 |
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