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Atomistry » Zinc » PDB 5sgz-5si2 » 5shr | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5sgz-5si2 » 5shr » |
Zinc in PDB 5shr: Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-AmineEnzymatic activity of Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine
All present enzymatic activity of Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine:
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine, PDB code: 5shr
was solved by
C.Joseph,
J.Benz,
A.Flohr,
M.G.Rudolph,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5shr:
The structure of Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine
(pdb code 5shr). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine, PDB code: 5shr: Jump to Zinc binding site number: 1; 2; 3; 4; Zinc binding site 1 out of 4 in 5shrGo back to Zinc Binding Sites List in 5shr
Zinc binding site 1 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine
Mono view Stereo pair view
Zinc binding site 2 out of 4 in 5shrGo back to Zinc Binding Sites List in 5shr
Zinc binding site 2 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine
Mono view Stereo pair view
Zinc binding site 3 out of 4 in 5shrGo back to Zinc Binding Sites List in 5shr
Zinc binding site 3 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine
Mono view Stereo pair view
Zinc binding site 4 out of 4 in 5shrGo back to Zinc Binding Sites List in 5shr
Zinc binding site 4 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with N-[(5, 8-Dimethyl-[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Methyl]-N,2-Dimethyl-5- Phenyl-1,2,4-Triazol-3-Amine
Mono view Stereo pair view
Reference:
A.Flohr,
D.Schlatter,
B.Kuhn,
M.G.Rudolph.
Crystal Structure of A Human Phosphodiesterase 10 Complex To Be Published.
Page generated: Mon Oct 28 05:34:36 2024
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