Zinc in PDB 5lx9: Crystal Structure of Human Adiponectin Receptor 2 in Complex with A C18 Free Fatty Acid at 2.4 Angstrom Resolution

The structure of Crystal Structure of Human Adiponectin Receptor 2 in Complex with A C18 Free Fatty Acid at 2.4 Angstrom Resolution, PDB code: 5lx9 was solved by I.Vasiliauskaite-Brooks, C.Leyrat, F.Hoh, S.Granier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	101.13 / 2.40
Space group	P 21 2 21
Cell size a, b, c (Å), α, β, γ (°)	74.578, 101.128, 111.577, 90.00, 90.00, 90.00
R / Rfree (%)	18.1 / 20.5

The binding sites of Zinc atom in the Crystal Structure of Human Adiponectin Receptor 2 in Complex with A C18 Free Fatty Acid at 2.4 Angstrom Resolution (pdb code 5lx9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Adiponectin Receptor 2 in Complex with A C18 Free Fatty Acid at 2.4 Angstrom Resolution, PDB code: 5lx9:

Zinc binding site 1 out of 1 in the Crystal Structure of Human Adiponectin Receptor 2 in Complex with A C18 Free Fatty Acid at 2.4 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Adiponectin Receptor 2 in Complex with A C18 Free Fatty Acid at 2.4 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:35.5 occ:1.00 NE2 A:HIS352 1.9 32.5 1.0 O A:HOH506 2.0 48.1 1.0 NE2 A:HIS348 2.1 33.6 1.0 NE2 A:HIS202 2.2 33.2 1.0 CE1 A:HIS352 2.8 32.6 1.0 O1 A:OLA402 3.0 52.7 1.0 CE1 A:HIS202 3.0 33.2 1.0 CE1 A:HIS348 3.0 33.3 1.0 CD2 A:HIS352 3.1 32.8 1.0 CD2 A:HIS348 3.1 33.9 1.0 CD2 A:HIS202 3.3 33.9 1.0 O2 A:OLA402 3.5 56.8 1.0 C1 A:OLA402 3.6 53.8 1.0 ND1 A:HIS352 4.0 33.6 1.0 OG A:SER198 4.1 38.2 1.0 CG A:HIS352 4.1 32.0 1.0 OD2 A:ASP219 4.2 45.0 1.0 ND1 A:HIS348 4.2 34.5 1.0 CG A:HIS348 4.2 32.3 1.0 ND1 A:HIS202 4.2 34.8 1.0 OD1 A:ASP219 4.3 35.8 1.0 CG A:HIS202 4.3 33.1 1.0 O A:HOH590 4.4 41.5 1.0 CG A:ASP219 4.7 36.9 1.0

I.Vasiliauskaite-Brooks, R.Sounier, P.Rochaix, G.Bellot, M.Fortier, F.Hoh, L.De Colibus, C.Bechara, E.M.Saied, C.Arenz, C.Leyrat, S.Granier. Structural Insights Into Adiponectin Receptors Suggest Ceramidase Activity. Nature V. 6 120 2017.
ISSN: ISSN 0028-0836
PubMed: 28329765
DOI: 10.1038/NATURE21714