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Atomistry » Zinc » PDB 5lbt-5ll9 » 5ljt » |
Zinc in PDB 5ljt: Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-((1-Phenyl-1H-1,2,3-Triazol-4-Yl)Methoxy)Benzenesulfonamide InhibitorEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-((1-Phenyl-1H-1,2,3-Triazol-4-Yl)Methoxy)Benzenesulfonamide Inhibitor
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-((1-Phenyl-1H-1,2,3-Triazol-4-Yl)Methoxy)Benzenesulfonamide Inhibitor:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-((1-Phenyl-1H-1,2,3-Triazol-4-Yl)Methoxy)Benzenesulfonamide Inhibitor, PDB code: 5ljt
was solved by
M.Ferraroni,
C.Supuran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-((1-Phenyl-1H-1,2,3-Triazol-4-Yl)Methoxy)Benzenesulfonamide Inhibitor
(pdb code 5ljt). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-((1-Phenyl-1H-1,2,3-Triazol-4-Yl)Methoxy)Benzenesulfonamide Inhibitor, PDB code: 5ljt: Zinc binding site 1 out of 1 in 5ljtGo back to Zinc Binding Sites List in 5ljt
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the 4-((1-Phenyl-1H-1,2,3-Triazol-4-Yl)Methoxy)Benzenesulfonamide Inhibitor
Mono view Stereo pair view
Reference:
A.Nocentini,
M.Ferraroni,
F.Carta,
M.Ceruso,
P.Gratteri,
C.Lanzi,
E.Masini,
C.T.Supuran.
Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations. J. Med. Chem. V. 59 10692 2016.
Page generated: Wed Dec 16 06:29:19 2020
ISSN: ISSN 1520-4804 PubMed: 27933963 DOI: 10.1021/ACS.JMEDCHEM.6B01389 |
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