Zinc in PDB 5k1b: Crystal Structure of the UAF1/USP12 Complex in F222 Space Group

All present enzymatic activity of Crystal Structure of the UAF1/USP12 Complex in F222 Space Group:
3.4.19.12;

The structure of Crystal Structure of the UAF1/USP12 Complex in F222 Space Group, PDB code: 5k1b was solved by H.Li, A.D.D'andrea, N.Zheng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 3.30
Space group	F 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	120.958, 158.929, 234.584, 90.00, 90.00, 90.00
R / Rfree (%)	23.5 / 28.6

The binding sites of Zinc atom in the Crystal Structure of the UAF1/USP12 Complex in F222 Space Group (pdb code 5k1b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the UAF1/USP12 Complex in F222 Space Group, PDB code: 5k1b:

Zinc binding site 1 out of 1 in the Crystal Structure of the UAF1/USP12 Complex in F222 Space Group


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the UAF1/USP12 Complex in F222 Space Group within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:0.6 occ:1.00 SG A:CYS233 1.7 0.4 1.0 SG A:CYS236 1.7 0.8 1.0 SG A:CYS189 2.1 0.5 1.0 SG A:CYS186 2.2 0.5 1.0 CB A:CYS186 2.7 0.1 1.0 CB A:CYS233 3.2 0.3 1.0 CB A:CYS236 3.5 1.0 1.0 CB A:CYS189 3.7 0.8 1.0 OG1 A:THR188 3.8 0.6 1.0 N A:CYS189 4.0 0.8 1.0 CA A:CYS186 4.2 0.2 1.0 N A:CYS236 4.2 0.1 1.0 CA A:CYS189 4.4 0.0 1.0 CA A:CYS233 4.5 0.5 1.0 CA A:CYS236 4.5 0.5 1.0 CB A:GLU235 4.5 0.1 1.0 CB A:THR191 4.7 0.1 1.0 OG1 A:THR191 4.7 0.6 1.0 C A:CYS186 4.8 0.5 1.0

H.Li, K.S.Lim, H.Kim, T.R.Hinds, U.Jo, H.Mao, C.E.Weller, J.Sun, C.Chatterjee, A.D.D'andrea, N.Zheng. Allosteric Activation of Ubiquitin-Specific Proteases By Beta-Propeller Proteins UAF1 and WDR20. Mol.Cell V. 63 249 2016.
ISSN: ISSN 1097-2765
PubMed: 27373336
DOI: 10.1016/J.MOLCEL.2016.05.031