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Zinc in PDB 5jwl: Factor Inhibiting Hif D201E in Complex with Zn, and Alpha- Ketoglutarate

Enzymatic activity of Factor Inhibiting Hif D201E in Complex with Zn, and Alpha- Ketoglutarate

All present enzymatic activity of Factor Inhibiting Hif D201E in Complex with Zn, and Alpha- Ketoglutarate:
1.14.11.30;

Protein crystallography data

The structure of Factor Inhibiting Hif D201E in Complex with Zn, and Alpha- Ketoglutarate, PDB code: 5jwl was solved by C.Y.Taabazuing, S.C.Garman, S.Eron, M.J.Knapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 32.56 / 2.40
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 86.131, 86.131, 149.213, 90.00, 90.00, 90.00
R / Rfree (%) 18 / 22.6

Zinc Binding Sites:

The binding sites of Zinc atom in the Factor Inhibiting Hif D201E in Complex with Zn, and Alpha- Ketoglutarate (pdb code 5jwl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Factor Inhibiting Hif D201E in Complex with Zn, and Alpha- Ketoglutarate, PDB code: 5jwl:

Zinc binding site 1 out of 1 in 5jwl

Go back to Zinc Binding Sites List in 5jwl
Zinc binding site 1 out of 1 in the Factor Inhibiting Hif D201E in Complex with Zn, and Alpha- Ketoglutarate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Factor Inhibiting Hif D201E in Complex with Zn, and Alpha- Ketoglutarate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn403

b:51.1
occ:1.00
O2 A:AKG401 1.9 50.2 1.0
OE1 A:GLU201 2.0 33.3 1.0
O5 A:AKG401 2.0 43.2 1.0
NE2 A:HIS199 2.2 42.0 1.0
NE2 A:HIS279 2.3 43.9 1.0
O A:HOH503 2.3 55.7 1.0
C1 A:AKG401 2.6 43.4 1.0
C2 A:AKG401 2.6 43.5 1.0
CD A:GLU201 2.9 41.9 1.0
CE1 A:HIS199 3.1 43.2 1.0
CD2 A:HIS279 3.2 43.8 1.0
OE2 A:GLU201 3.2 39.5 1.0
CD2 A:HIS199 3.3 37.7 1.0
CE1 A:HIS279 3.3 41.6 1.0
O1 A:AKG401 3.8 45.3 1.0
C3 A:AKG401 4.1 41.4 1.0
O A:HOH575 4.1 40.7 1.0
ND1 A:HIS199 4.2 44.5 1.0
CZ2 A:TRP296 4.3 67.9 1.0
O2 A:PEG402 4.3 88.1 1.0
CG A:GLU201 4.3 43.6 1.0
CG A:HIS279 4.3 43.1 1.0
CG A:HIS199 4.3 39.4 1.0
ND1 A:HIS279 4.4 46.7 1.0
C3 A:PEG402 4.6 89.9 1.0
C4 A:AKG401 4.8 43.8 1.0
CB A:GLU201 5.0 46.8 1.0

Reference:

J.A.Hangasky, C.Y.Taabazuing, C.Martin, S.Eron, S.C.Garman, M.J.Knapp. Factor Inhibiting Hif D201E in Complex with Zn, and Alpha-Ketoglutarate To Be Published.
Page generated: Wed Dec 16 06:25:58 2020

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