Zinc in PDB 5hnr: The X-Ray Structure of Octameric Human Native 5-Aminolaevulinic Acid Dehydratase.

All present enzymatic activity of The X-Ray Structure of Octameric Human Native 5-Aminolaevulinic Acid Dehydratase.:
4.2.1.24;

The structure of The X-Ray Structure of Octameric Human Native 5-Aminolaevulinic Acid Dehydratase., PDB code: 5hnr was solved by N.L.Mills-Davies, D.Thompson, P.M.Shoolingin-Jordan, P.T.Erskine, J.B.Cooper, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.38 / 2.83
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	125.530, 125.530, 200.910, 90.00, 90.00, 90.00
R / Rfree (%)	16.5 / 23.8

The binding sites of Zinc atom in the The X-Ray Structure of Octameric Human Native 5-Aminolaevulinic Acid Dehydratase. (pdb code 5hnr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the The X-Ray Structure of Octameric Human Native 5-Aminolaevulinic Acid Dehydratase., PDB code: 5hnr:

Zinc binding site 1 out of 1 in the The X-Ray Structure of Octameric Human Native 5-Aminolaevulinic Acid Dehydratase.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The X-Ray Structure of Octameric Human Native 5-Aminolaevulinic Acid Dehydratase. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:90.6 occ:1.00 O A:HOH662 2.0 70.4 1.0 SG A:CYS132 2.4 98.7 1.0 SG A:CYS124 2.4 98.5 1.0 SG A:CYS122 2.4 0.4 1.0 CB A:CYS124 3.3 98.2 1.0 CB A:CYS132 3.3 0.3 1.0 CB A:CYS122 3.5 95.0 1.0 CA A:CYS132 3.9 0.9 1.0 OG A:SER168 4.0 45.4 1.0 N A:CYS124 4.2 92.5 1.0 CA A:CYS124 4.3 98.7 1.0 O A:SER168 4.4 48.1 1.0 CA A:ASP169 4.6 67.7 1.0 C A:SER168 4.6 53.3 1.0 N A:ASP169 4.6 61.5 1.0 N A:CYS132 4.7 0.2 1.0 CB A:SER168 4.9 47.1 1.0 CD A:PRO125 4.9 0.7 1.0 CA A:CYS122 4.9 88.6 1.0

N.Mills-Davies, D.Butler, E.Norton, D.Thompson, M.Sarwar, J.Guo, R.Gill, N.Azim, A.Coker, S.P.Wood, P.T.Erskine, L.Coates, J.B.Cooper, N.Rashid, M.Akhtar, P.M.Shoolingin-Jordan. Structural Studies of Substrate and Product Complexes of 5-Aminolaevulinic Acid Dehydratase From Humans, Escherichia Coli and the Hyperthermophile Pyrobaculum Calidifontis. Acta Crystallogr D Struct V. 73 9 2017BIOL.
ISSN: ISSN 2059-7983
PubMed: 28045381
DOI: 10.1107/S2059798316019525