Zinc in PDB 5goy: The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine

All present enzymatic activity of The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine:
6.1.1.10;

The structure of The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine, PDB code: 5goy was solved by H.J.Lee, H.Y.Cho, B.S.Kang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.70 / 2.28
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	65.539, 93.133, 122.482, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 24.2

The binding sites of Zinc atom in the The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine (pdb code 5goy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine, PDB code: 5goy:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn901 b:44.9 occ:1.00 SG A:CYS438 2.3 49.1 1.0 SG A:CYS389 2.3 44.0 1.0 SG A:CYS435 2.4 50.8 1.0 SG A:CYS392 2.6 49.8 1.0 CB A:CYS435 3.0 43.7 1.0 CB A:CYS389 3.4 43.3 1.0 CB A:CYS392 3.4 46.1 1.0 CB A:CYS438 3.5 47.4 1.0 OG A:SER440 3.8 48.4 1.0 N A:CYS438 3.8 55.5 1.0 N A:CYS392 4.0 51.8 1.0 CA A:CYS438 4.2 51.4 1.0 CA A:CYS392 4.3 47.8 1.0 CB A:VAL437 4.5 52.4 1.0 CA A:CYS435 4.5 45.8 1.0 O A:CYS435 4.6 56.2 1.0 CB A:HIS391 4.8 46.3 1.0 CA A:CYS389 4.8 47.5 1.0 C A:CYS435 4.8 51.4 1.0 C A:CYS438 4.8 55.2 1.0 C A:VAL437 4.9 53.2 1.0 N A:ARG439 4.9 50.5 1.0 CB A:SER440 4.9 40.4 1.0 N A:SER440 5.0 41.4 1.0

Zinc binding site 2 out of 2 in the The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn902 b:37.9 occ:1.00 SG A:CYS405 2.3 29.5 1.0 SG A:CYS408 2.3 35.8 1.0 SG A:CYS421 2.4 37.7 1.0 SG A:CYS418 2.4 34.3 1.0 CB A:CYS405 3.1 35.6 1.0 CB A:CYS418 3.3 32.3 1.0 CB A:CYS408 3.3 35.8 1.0 CB A:CYS421 3.3 32.7 1.0 N A:CYS408 3.7 37.8 1.0 N A:CYS421 3.9 36.5 1.0 CA A:CYS408 4.0 37.6 1.0 CA A:CYS421 4.2 34.3 1.0 CB A:TYR410 4.3 45.0 1.0 CB A:PHE407 4.5 35.6 1.0 CA A:CYS405 4.6 40.8 1.0 C A:PHE407 4.6 39.0 1.0 C A:CYS408 4.7 35.2 1.0 N A:GLY409 4.7 38.3 1.0 CB A:LYS420 4.7 43.8 1.0 CA A:CYS418 4.7 41.7 1.0 N A:TYR410 4.7 39.6 1.0 C A:LYS420 4.9 37.7 1.0 CA A:PHE407 4.9 37.1 1.0 N A:PHE407 4.9 35.0 1.0 C A:CYS421 4.9 42.4 1.0

H.J.Lee, H.Y.Cho, B.S.Kang. The Crystal Structure of Human Cytosolic Methionyl-Trna Synthetase in Complex with Methionine To Be Published.