Atomistry » Zinc » PDB 5adr-5amb » 5adr
Atomistry »
  Zinc »
    PDB 5adr-5amb »
      5adr »

Zinc in PDB 5adr: Crystal Structure of Human Tankyrase 2 in Complex with OD38

Protein crystallography data

The structure of Crystal Structure of Human Tankyrase 2 in Complex with OD38, PDB code: 5adr was solved by T.Haikarainen, L.Lehtio, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.32 / 2.10
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 65.570, 65.570, 121.920, 90.00, 90.00, 90.00
R / Rfree (%) 18.725 / 23.875

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human Tankyrase 2 in Complex with OD38 (pdb code 5adr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Tankyrase 2 in Complex with OD38, PDB code: 5adr:

Zinc binding site 1 out of 1 in 5adr

Go back to Zinc Binding Sites List in 5adr
Zinc binding site 1 out of 1 in the Crystal Structure of Human Tankyrase 2 in Complex with OD38


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Tankyrase 2 in Complex with OD38 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2116

b:23.2
occ:1.00
ND1 A:HIS1084 2.2 27.5 1.0
SG A:CYS1089 2.2 18.6 1.0
SG A:CYS1092 2.3 24.4 1.0
SG A:CYS1081 2.3 22.0 1.0
CE1 A:HIS1084 3.1 29.1 1.0
CB A:CYS1081 3.2 24.5 1.0
CG A:HIS1084 3.2 28.5 1.0
CB A:CYS1089 3.2 19.5 1.0
CB A:CYS1092 3.3 23.0 1.0
CB A:HIS1084 3.5 26.9 1.0
N A:HIS1084 3.8 27.8 1.0
N A:CYS1092 4.0 22.1 1.0
CA A:CYS1092 4.2 22.5 1.0
NE2 A:HIS1084 4.2 31.0 1.0
CB A:VAL1083 4.2 29.9 1.0
CA A:HIS1084 4.2 25.8 1.0
CD2 A:HIS1084 4.3 28.8 1.0
CA A:CYS1081 4.6 25.5 1.0
CA A:CYS1089 4.6 20.1 1.0
C A:VAL1083 4.6 28.9 1.0
N A:VAL1083 4.8 31.6 1.0
CA A:VAL1083 4.8 31.0 1.0
CB A:ILE1091 4.8 22.9 1.0
CG1 A:VAL1083 4.9 29.4 1.0
O A:HOH3121 4.9 21.9 1.0
C A:CYS1081 5.0 28.2 1.0

Reference:

T.Haikarainen, J.Waaler, A.Ignatev, Y.Nkizinkiko, H.Venkannagari, E.Obaji, S.Krauss, L.Lehtio. Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors. Bioorg.Med.Chem.Lett. V. 26 328 2016.
ISSN: ISSN 0960-894X
PubMed: 26706174
DOI: 10.1016/J.BMCL.2015.12.018
Page generated: Wed Dec 16 06:02:53 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy