Atomistry » Zinc » PDB 5ab2-5aeb » 5adh
Atomistry »
  Zinc »
    PDB 5ab2-5aeb »
      5adh »

Zinc in PDB 5adh: Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode

Enzymatic activity of Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode

All present enzymatic activity of Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode:
1.1.1.1;

Protein crystallography data

The structure of Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode, PDB code: 5adh was solved by H.Eklund, T.A.Jones, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 2.90
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 56.000, 75.200, 181.700, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Zinc Binding Sites:

The binding sites of Zinc atom in the Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode (pdb code 5adh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode, PDB code: 5adh:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 5adh

Go back to Zinc Binding Sites List in 5adh
Zinc binding site 1 out of 2 in the Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn375

b:19.0
occ:1.00
O A:HOH419 2.2 19.0 1.0
NE2 A:HIS67 2.2 19.0 1.0
SG A:CYS46 2.3 19.0 1.0
SG A:CYS174 2.3 19.0 1.0
CE1 A:HIS67 3.1 19.0 1.0
CD2 A:HIS67 3.3 19.0 1.0
CB A:CYS46 3.3 19.0 1.0
CB A:CYS174 3.4 19.0 1.0
O A:HOH404 4.1 19.0 1.0
O A:HOH429 4.1 19.0 1.0
ND1 A:HIS67 4.3 19.0 1.0
CB A:SER48 4.3 19.0 1.0
CG A:HIS67 4.4 19.0 1.0
O A:HOH403 4.5 19.0 1.0
OG A:SER48 4.6 19.0 1.0
O A:HOH668 4.7 19.0 1.0
CA A:CYS174 4.7 19.0 1.0
CA A:CYS46 4.8 19.0 1.0
CE1 A:PHE93 5.0 19.0 1.0
N A:GLY175 5.0 19.0 1.0

Zinc binding site 2 out of 2 in 5adh

Go back to Zinc Binding Sites List in 5adh
Zinc binding site 2 out of 2 in the Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn376

b:19.0
occ:1.00
SG A:CYS100 2.2 19.0 1.0
SG A:CYS97 2.3 19.0 1.0
SG A:CYS103 2.3 19.0 1.0
SG A:CYS111 2.4 19.0 1.0
CB A:CYS103 3.3 19.0 1.0
CB A:CYS97 3.3 19.0 1.0
CB A:CYS100 3.4 19.0 1.0
CB A:CYS111 3.5 19.0 1.0
N A:CYS97 3.5 19.0 1.0
N A:CYS100 3.7 19.0 1.0
N A:GLY98 3.8 19.0 1.0
CA A:CYS97 3.8 19.0 1.0
CA A:CYS111 3.9 19.0 1.0
N A:LEU112 4.1 19.0 1.0
CA A:CYS100 4.1 19.0 1.0
C A:CYS97 4.2 19.0 1.0
N A:LYS99 4.3 19.0 1.0
N A:CYS103 4.3 19.0 1.0
CA A:CYS103 4.3 19.0 1.0
C A:GLN96 4.4 19.0 1.0
C A:CYS111 4.5 19.0 1.0
CA A:GLY98 4.7 19.0 1.0
CA A:GLN96 4.8 19.0 1.0
C A:LYS99 4.8 19.0 1.0
N A:LYS113 4.9 19.0 1.0
C A:GLY98 4.9 19.0 1.0
C A:CYS100 4.9 19.0 1.0
CG A:LYS113 5.0 19.0 1.0

Reference:

F.Colonna-Cesari, D.Perahia, M.Karplus, H.Eklund, C.I.Braden, O.Tapia. Interdomain Motion in Liver Alcohol Dehydrogenase. Structural and Energetic Analysis of the Hinge Bending Mode. J.Biol.Chem. V. 261 15273 1986.
ISSN: ISSN 0021-9258
PubMed: 3771574
Page generated: Wed Dec 16 06:02:40 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy