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Atomistry » Zinc » PDB 4zvm-5a1f » 4zx1 » |
Zinc in PDB 4zx1: Engineered Carbonic Anhydrase IX Mimic in Complex with A Glucosyl Sulfamate InhibitorEnzymatic activity of Engineered Carbonic Anhydrase IX Mimic in Complex with A Glucosyl Sulfamate Inhibitor
All present enzymatic activity of Engineered Carbonic Anhydrase IX Mimic in Complex with A Glucosyl Sulfamate Inhibitor:
4.2.1.1; Protein crystallography data
The structure of Engineered Carbonic Anhydrase IX Mimic in Complex with A Glucosyl Sulfamate Inhibitor, PDB code: 4zx1
was solved by
B.P.Mahon,
C.L.Lomelino,
A.L.Salguero,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Engineered Carbonic Anhydrase IX Mimic in Complex with A Glucosyl Sulfamate Inhibitor
(pdb code 4zx1). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Engineered Carbonic Anhydrase IX Mimic in Complex with A Glucosyl Sulfamate Inhibitor, PDB code: 4zx1: Zinc binding site 1 out of 1 in 4zx1Go back to Zinc Binding Sites List in 4zx1
Zinc binding site 1 out
of 1 in the Engineered Carbonic Anhydrase IX Mimic in Complex with A Glucosyl Sulfamate Inhibitor
Mono view Stereo pair view
Reference:
B.P.Mahon,
C.L.Lomelino,
J.Moeker,
G.M.Rankin,
J.M.Driscoll,
A.L.Salguero,
M.A.Pinard,
D.Vullo,
C.T.Supuran,
S.A.Poulsen,
R.Mckenna.
Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates J. Med. Chem. V. 58 6630 2015.
Page generated: Sun Oct 27 12:07:26 2024
ISSN: ISSN 0022-2623 PubMed: 26203869 DOI: 10.1021/ACS.JMEDCHEM.5B00845 |
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