Zinc in PDB 4ys9: Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal)

The structure of Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal), PDB code: 4ys9 was solved by V.A.Zhemkov, M.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	59.67 / 2.00
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	59.670, 59.670, 135.165, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 22.3

The binding sites of Zinc atom in the Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal) (pdb code 4ys9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal), PDB code: 4ys9:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn502 b:28.7 occ:1.00 O B:HOH663 1.8 23.3 1.0 OD2 B:ASP164 2.1 27.4 1.0 OD1 B:ASP164 2.6 26.3 1.0 CG B:ASP164 2.7 27.8 1.0 CD B:LYS251 3.9 32.3 1.0 CB B:ASP164 4.2 28.2 1.0 O B:HOH622 4.6 34.4 1.0 O B:ASP164 4.6 31.3 1.0 CE B:LYS251 4.7 31.8 1.0 NE2 B:GLN253 4.9 30.7 1.0 CB B:LYS251 5.0 30.5 1.0 CG B:LYS251 5.0 31.5 1.0

Zinc binding site 2 out of 4 in the Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn503 b:38.6 occ:1.00 OE2 B:GLU278 2.2 36.1 1.0 OE1 B:GLU278 2.7 36.1 1.0 O B:HOH688 2.7 37.9 1.0 CD B:GLU278 2.8 36.7 1.0 O B:HOH685 3.3 40.2 1.0 CG B:GLU278 4.3 35.0 1.0 OD1 B:ASN282 4.5 38.4 1.0

Zinc binding site 3 out of 4 in the Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn504 b:77.8 occ:1.00 NE2 B:HIS39 3.7 29.4 1.0 O B:VAL37 3.8 31.7 1.0 CD2 B:HIS39 3.8 29.4 1.0 CD1 B:TYR17 3.9 29.5 1.0 CE1 B:TYR17 4.1 30.3 1.0 O B:HOH626 4.8 33.8 1.0 C B:VAL37 4.8 31.4 1.0 ND2 B:ASN18 4.8 28.4 1.0 CG B:TYR17 4.9 29.3 1.0 CE1 B:HIS39 4.9 29.8 1.0 O B:HOH628 5.0 33.8 1.0

Zinc binding site 4 out of 4 in the Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Ataxin-3 Carboxy-Terminal Region - Crystal C1 (Tetragonal) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn505 b:90.6 occ:1.00 O B:HOH689 2.5 61.4 1.0 NE2 B:HIS203 3.8 36.2 1.0 O B:PRO133 3.8 36.6 1.0 CE1 B:HIS203 4.0 36.2 1.0 C B:PRO133 4.0 34.5 1.0 CB B:PRO133 4.2 34.0 1.0 N B:ALA134 4.3 34.3 1.0 CA B:ALA134 4.5 35.5 1.0 CD B:LYS137 4.6 39.4 1.0 O B:HOH607 4.6 43.5 1.0 CB B:LYS137 4.6 39.5 1.0 CA B:PRO133 4.7 34.0 1.0

V.A.Zhemkov, A.A.Kulminskaya, I.B.Bezprozvanny, M.Kim. The 2.2-Angstrom Resolution Crystal Structure of the Carboxy-Terminal Region of Ataxin-3. Febs Open Bio V. 6 168 2016.
ISSN: ESSN 2211-5463
PubMed: 27047745
DOI: 10.1002/2211-5463.12029