Atomistry » Zinc » PDB 4ufy-4upt » 4uov
Atomistry »
  Zinc »
    PDB 4ufy-4upt »
      4uov »

Zinc in PDB 4uov: The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.

Enzymatic activity of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.

All present enzymatic activity of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.:
4.2.1.1;

Protein crystallography data

The structure of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability., PDB code: 4uov was solved by P.James, M.Isupov, C.Sayer, S.Berg, M.Lioliou, H.Kotlar, J.Littlechild, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.01 / 1.85
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 163.750, 283.020, 52.170, 90.00, 90.00, 90.00
R / Rfree (%) 17.181 / 20.404

Other elements in 4uov:

The structure of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability. also contains other interesting chemical elements:

Chlorine (Cl) 15 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability. (pdb code 4uov). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability., PDB code: 4uov:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in 4uov

Go back to Zinc Binding Sites List in 4uov
Zinc binding site 1 out of 6 in the The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn298

b:19.4
occ:1.00
 N1 A:AZM299 2.0 21.6 1.0
NE2 A:HIS114 2.1 18.7 1.0
NE2 A:HIS112 2.1 19.4 1.0
ND1 A:HIS131 2.1 14.7 1.0
CD2 A:HIS112 3.0 18.6 1.0
CE1 A:HIS131 3.0 14.1 1.0
CE1 A:HIS114 3.0 20.7 1.0
CD2 A:HIS114 3.1 16.6 1.0
O2 A:AZM299 3.1 21.5 1.0
S1 A:AZM299 3.1 23.4 1.0
CE1 A:HIS112 3.1 19.8 1.0
CG A:HIS131 3.2 14.6 1.0
CB A:HIS131 3.6 14.1 1.0
OE1 A:GLU118 3.8 19.1 1.0
OG1 A:THR198 4.0 17.2 1.0
NE2 A:HIS131 4.1 15.7 1.0
CG A:HIS112 4.1 19.3 1.0
ND1 A:HIS114 4.2 18.0 1.0
C1 A:AZM299 4.2 28.6 1.0
ND1 A:HIS112 4.2 19.2 1.0
CG A:HIS114 4.2 18.0 1.0
O1 A:AZM299 4.2 23.6 1.0
CD2 A:HIS131 4.2 13.2 1.0
CD A:GLU118 4.8 20.0 1.0
N3 A:AZM299 4.8 31.1 1.0

Zinc binding site 2 out of 6 in 4uov

Go back to Zinc Binding Sites List in 4uov
Zinc binding site 2 out of 6 in the The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn298

b:17.4
occ:1.00
 N1 B:AZM299 1.9 19.5 1.0
ND1 B:HIS131 2.1 13.8 1.0
NE2 B:HIS114 2.1 15.1 1.0
NE2 B:HIS112 2.1 18.2 1.0
CE1 B:HIS131 2.9 14.7 1.0
CD2 B:HIS114 3.0 15.8 1.0
CD2 B:HIS112 3.0 19.1 1.0
O2 B:AZM299 3.1 17.9 1.0
S1 B:AZM299 3.1 21.2 1.0
CE1 B:HIS112 3.1 19.7 1.0
CE1 B:HIS114 3.1 17.7 1.0
CG B:HIS131 3.2 12.2 1.0
CB B:HIS131 3.6 13.1 1.0
OE1 B:GLU118 3.8 17.9 1.0
OG1 B:THR198 4.0 18.0 1.0
NE2 B:HIS131 4.1 12.8 1.0
O1 B:AZM299 4.1 22.0 1.0
C1 B:AZM299 4.2 29.1 1.0
CG B:HIS114 4.2 13.5 1.0
CG B:HIS112 4.2 17.3 1.0
ND1 B:HIS114 4.2 16.1 1.0
ND1 B:HIS112 4.2 17.2 1.0
CD2 B:HIS131 4.2 13.5 1.0
CD B:GLU118 4.8 18.0 1.0
N3 B:AZM299 4.9 33.6 1.0

Zinc binding site 3 out of 6 in 4uov

Go back to Zinc Binding Sites List in 4uov
Zinc binding site 3 out of 6 in the The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability. within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn298

b:20.3
occ:1.00
 N1 C:AZM299 2.0 21.8 1.0
NE2 C:HIS112 2.0 21.6 1.0
ND1 C:HIS131 2.1 16.4 1.0
NE2 C:HIS114 2.1 20.3 1.0
CE1 C:HIS131 2.9 14.9 1.0
CD2 C:HIS112 3.0 20.5 1.0
CD2 C:HIS114 3.0 19.5 1.0
O2 C:AZM299 3.1 17.7 1.0
CE1 C:HIS112 3.1 21.0 1.0
S1 C:AZM299 3.1 23.0 1.0
CG C:HIS131 3.2 15.3 1.0
CE1 C:HIS114 3.2 19.4 1.0
O C:HOH2162 3.5 47.1 1.0
CB C:HIS131 3.6 15.4 1.0
OE1 C:GLU118 3.8 21.2 1.0
OG1 C:THR198 4.0 17.3 1.0
NE2 C:HIS131 4.1 16.3 1.0
CG C:HIS112 4.1 20.4 1.0
ND1 C:HIS112 4.1 20.9 1.0
C1 C:AZM299 4.1 25.5 1.0
O1 C:AZM299 4.2 23.8 1.0
CG C:HIS114 4.2 18.8 1.0
CD2 C:HIS131 4.2 15.4 1.0
ND1 C:HIS114 4.2 20.6 1.0
CD C:GLU118 4.8 19.5 1.0
N3 C:AZM299 4.8 28.4 1.0

Zinc binding site 4 out of 6 in 4uov

Go back to Zinc Binding Sites List in 4uov
Zinc binding site 4 out of 6 in the The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability. within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn298

b:20.1
occ:1.00
 N1 D:AZM299 2.0 24.0 1.0
NE2 D:HIS112 2.1 19.8 1.0
ND1 D:HIS131 2.1 17.8 1.0
NE2 D:HIS114 2.1 17.1 1.0
CD2 D:HIS112 2.9 22.4 1.0
CE1 D:HIS131 3.0 16.8 1.0
CD2 D:HIS114 3.0 16.9 1.0
O2 D:AZM299 3.0 18.7 1.0
S1 D:AZM299 3.1 25.8 1.0
CE1 D:HIS114 3.1 19.4 1.0
CE1 D:HIS112 3.2 24.4 1.0
CG D:HIS131 3.2 15.6 1.0
O D:HOH2119 3.5 52.1 1.0
CB D:HIS131 3.6 16.6 1.0
OE1 D:GLU118 3.9 20.7 1.0
OG1 D:THR198 4.1 19.8 1.0
CG D:HIS112 4.1 25.6 1.0
NE2 D:HIS131 4.1 16.2 1.0
C1 D:AZM299 4.2 28.3 1.0
CG D:HIS114 4.2 19.5 1.0
O1 D:AZM299 4.2 25.7 1.0
ND1 D:HIS112 4.2 21.4 1.0
ND1 D:HIS114 4.2 17.3 1.0
CD2 D:HIS131 4.2 15.4 1.0
N3 D:AZM299 4.8 32.7 1.0
CD D:GLU118 4.8 20.5 1.0

Zinc binding site 5 out of 6 in 4uov

Go back to Zinc Binding Sites List in 4uov
Zinc binding site 5 out of 6 in the The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability. within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn298

b:18.8
occ:1.00
 N1 E:AZM299 1.9 21.7 1.0
NE2 E:HIS112 2.0 16.7 1.0
NE2 E:HIS114 2.1 18.7 1.0
ND1 E:HIS131 2.1 14.8 1.0
CD2 E:HIS112 2.9 18.4 1.0
CE1 E:HIS131 3.0 14.2 1.0
O2 E:AZM299 3.0 18.3 1.0
CD2 E:HIS114 3.0 18.9 1.0
S1 E:AZM299 3.1 22.3 1.0
CE1 E:HIS112 3.1 17.6 1.0
CE1 E:HIS114 3.1 18.4 1.0
CG E:HIS131 3.2 14.3 1.0
CB E:HIS131 3.6 14.7 1.0
OE1 E:GLU118 3.9 19.6 1.0
OG1 E:THR198 4.0 18.7 1.0
CG E:HIS112 4.1 16.8 1.0
C1 E:AZM299 4.1 25.7 1.0
ND1 E:HIS112 4.1 17.9 1.0
O1 E:AZM299 4.2 24.7 1.0
NE2 E:HIS131 4.2 14.4 1.0
CG E:HIS114 4.2 17.6 1.0
ND1 E:HIS114 4.2 18.9 1.0
CD2 E:HIS131 4.3 13.3 1.0
N3 E:AZM299 4.8 30.6 1.0
CD E:GLU118 4.8 22.3 1.0

Zinc binding site 6 out of 6 in 4uov

Go back to Zinc Binding Sites List in 4uov
Zinc binding site 6 out of 6 in the The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of The Structure of A Tetrameric Alpha-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides, Which Contribute to Its Thermostability. within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn298

b:17.1
occ:1.00
 N1 F:AZM299 1.9 19.6 1.0
ND1 F:HIS131 2.0 13.4 1.0
NE2 F:HIS112 2.1 15.5 1.0
NE2 F:HIS114 2.1 12.7 1.0
CE1 F:HIS131 2.9 14.1 1.0
CD2 F:HIS112 3.0 16.8 1.0
S1 F:AZM299 3.0 19.7 1.0
CD2 F:HIS114 3.1 15.7 1.0
O2 F:AZM299 3.1 18.4 1.0
CE1 F:HIS112 3.1 17.5 1.0
CE1 F:HIS114 3.1 16.0 1.0
CG F:HIS131 3.2 14.8 1.0
CB F:HIS131 3.6 11.4 1.0
OE1 F:GLU118 3.8 19.9 1.0
OG1 F:THR198 4.0 16.6 1.0
NE2 F:HIS131 4.1 14.2 1.0
C1 F:AZM299 4.1 25.2 1.0
O1 F:AZM299 4.2 17.8 1.0
CG F:HIS112 4.2 15.6 1.0
ND1 F:HIS112 4.2 15.5 1.0
CG F:HIS114 4.2 13.2 1.0
ND1 F:HIS114 4.2 12.8 1.0
CD2 F:HIS131 4.2 12.8 1.0
N3 F:AZM299 4.8 25.3 1.0
CD F:GLU118 4.9 18.3 1.0

Reference:

P.James, M.N.Isupov, C.Sayer, V.Saneei, S.Berg, M.Lioliou, H.Kotlar, J.Littlechild. The Structure of A Tetrameric [Alpha]-Carbonic Anhydrase From Thermovibrio Ammonificans Reveals A Core Formed Around Intermolecular Disulfides That Contribute to Its Thermostability Acta Crystallogr.,Sect.D V. 70 2607 2014.
ISSN: ISSN 0907-4449
PubMed: 25286845
DOI: 10.1107/S1399004714016526
Page generated: Sun Oct 27 09:12:58 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy