Atomistry » Zinc » PDB 4u3e-4uez » 4ubq
Atomistry »
  Zinc »
    PDB 4u3e-4uez »
      4ubq »

Zinc in PDB 4ubq: Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp.

Enzymatic activity of Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp.

All present enzymatic activity of Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp.:
3.5.2.6;

Protein crystallography data

The structure of Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp., PDB code: 4ubq was solved by Y.Yamaguchi, S.Matsueda, K.Matsunaga, N.Takashio, S.Toma-Fukai, Y.Yamagata, N.Shibata, J.Wachino, K.Shibayama, Y.Arakawa, H.Kurosaki, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.16 / 2.30
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 37.942, 68.488, 88.322, 90.00, 90.00, 90.00
R / Rfree (%) 23.2 / 29.9

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp. (pdb code 4ubq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp., PDB code: 4ubq:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4ubq

Go back to Zinc Binding Sites List in 4ubq
Zinc binding site 1 out of 2 in the Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn301

b:30.2
occ:1.00
ND1 A:HIS80 2.1 25.4 1.0
NE2 A:HIS140 2.1 24.8 1.0
NE2 A:HIS78 2.2 21.7 1.0
OXT A:ACT303 2.6 27.2 0.5
CD2 A:HIS140 2.9 24.3 1.0
CG A:HIS80 3.1 25.2 1.0
CD2 A:HIS78 3.1 23.3 1.0
CE1 A:HIS80 3.1 25.1 1.0
CE1 A:HIS78 3.2 22.0 1.0
CE1 A:HIS140 3.2 25.7 1.0
CB A:HIS80 3.3 25.3 1.0
C A:ACT303 3.4 27.5 0.5
ZN A:ZN302 3.5 38.2 0.3
OD1 A:ASP82 3.9 32.6 1.0
CH3 A:ACT303 3.9 27.3 0.5
SG A:CYS159 4.0 24.9 0.7
CG A:HIS140 4.2 24.8 1.0
O A:ACT303 4.2 27.6 0.5
CB A:CYS159 4.2 22.6 0.3
SG A:CYS159 4.2 22.0 0.3
NE2 A:HIS80 4.2 22.6 1.0
CD2 A:HIS80 4.2 24.5 1.0
ND1 A:HIS140 4.3 24.9 1.0
CB A:CYS159 4.3 23.0 0.7
CG A:HIS78 4.3 22.6 1.0
ND1 A:HIS78 4.3 22.2 1.0
OD2 A:ASP82 4.4 31.3 1.0
O A:HOH407 4.6 47.2 1.0
CG A:ASP82 4.6 28.7 1.0
CH3 A:ACT303 4.6 21.9 0.5
O A:ACT303 4.7 21.9 0.5
CG2 A:THR141 4.7 23.3 1.0
CA A:HIS80 4.8 25.2 1.0
C A:ACT303 5.0 22.1 0.5

Zinc binding site 2 out of 2 in 4ubq

Go back to Zinc Binding Sites List in 4ubq
Zinc binding site 2 out of 2 in the Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn302

b:38.2
occ:0.30
SG A:CYS159 1.9 24.9 0.7
SG A:CYS159 2.4 22.0 0.3
OD2 A:ASP82 2.5 31.3 1.0
NE2 A:HIS198 2.7 34.9 1.0
CB A:CYS159 3.2 22.6 0.3
O A:ACT303 3.2 21.9 0.5
CB A:CYS159 3.3 23.0 0.7
CH3 A:ACT303 3.3 21.9 0.5
CD2 A:HIS198 3.3 34.7 1.0
ZN A:ZN301 3.5 30.2 1.0
CH3 A:ACT303 3.5 27.3 0.5
CG A:ASP82 3.5 28.7 1.0
C A:ACT303 3.6 27.5 0.5
C A:ACT303 3.6 22.1 0.5
OD1 A:ASP82 3.9 32.6 1.0
CE1 A:HIS198 3.9 34.8 1.0
O A:ACT303 3.9 27.6 0.5
OXT A:ACT303 4.1 27.2 0.5
NE2 A:HIS140 4.2 24.8 1.0
NE2 A:HIS78 4.3 21.7 1.0
CE1 A:HIS78 4.3 22.0 1.0
CB A:SER197 4.3 32.1 1.0
CA A:CYS159 4.4 22.8 0.3
OG A:SER197 4.4 32.5 1.0
CE1 A:HIS140 4.5 25.7 1.0
CA A:CYS159 4.5 23.3 0.7
CG A:HIS198 4.6 34.4 1.0
CD A:LYS34 4.7 26.5 1.0
CE A:LYS34 4.8 26.1 1.0
NZ A:LYS162 4.8 28.1 1.0
CB A:ASP82 4.8 26.2 1.0
ND1 A:HIS198 4.9 34.0 1.0
OXT A:ACT303 4.9 21.9 0.5
CD2 A:HIS140 4.9 24.3 1.0

Reference:

Y.Yamaguchi, S.Matsueda, K.Matsunaga, N.Takashio, S.Toma-Fukai, Y.Yamagata, N.Shibata, J.Wachino, K.Shibayama, Y.Arakawa, H.Kurosaki. Crystal Structure of Imp-2 Metallo-Beta-Lactamase From Acinetobacter Spp.: Comparison of Active-Site Loop Structures Between Imp-1 and Imp-2 To Be Published.
Page generated: Wed Dec 16 05:48:05 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy