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Atomistry » Zinc » PDB 4tph-4u4t » 4u3b | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4tph-4u4t » 4u3b » |
Zinc in PDB 4u3b: Lpxc From A.Aaeolicus in Complex with the Mmp Inhibitor 4-[[4-(4- Chlorophenoxy)Phenyl]Sulfanylmethyl]Tetrahydropyran-4-Carbohydroxamic Acid - Compound 2Protein crystallography data
The structure of Lpxc From A.Aaeolicus in Complex with the Mmp Inhibitor 4-[[4-(4- Chlorophenoxy)Phenyl]Sulfanylmethyl]Tetrahydropyran-4-Carbohydroxamic Acid - Compound 2, PDB code: 4u3b
was solved by
N.B.Olivier,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4u3b:
The structure of Lpxc From A.Aaeolicus in Complex with the Mmp Inhibitor 4-[[4-(4- Chlorophenoxy)Phenyl]Sulfanylmethyl]Tetrahydropyran-4-Carbohydroxamic Acid - Compound 2 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Lpxc From A.Aaeolicus in Complex with the Mmp Inhibitor 4-[[4-(4- Chlorophenoxy)Phenyl]Sulfanylmethyl]Tetrahydropyran-4-Carbohydroxamic Acid - Compound 2
(pdb code 4u3b). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Lpxc From A.Aaeolicus in Complex with the Mmp Inhibitor 4-[[4-(4- Chlorophenoxy)Phenyl]Sulfanylmethyl]Tetrahydropyran-4-Carbohydroxamic Acid - Compound 2, PDB code: 4u3b: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4u3bGo back to Zinc Binding Sites List in 4u3b
Zinc binding site 1 out
of 2 in the Lpxc From A.Aaeolicus in Complex with the Mmp Inhibitor 4-[[4-(4- Chlorophenoxy)Phenyl]Sulfanylmethyl]Tetrahydropyran-4-Carbohydroxamic Acid - Compound 2
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4u3bGo back to Zinc Binding Sites List in 4u3b
Zinc binding site 2 out
of 2 in the Lpxc From A.Aaeolicus in Complex with the Mmp Inhibitor 4-[[4-(4- Chlorophenoxy)Phenyl]Sulfanylmethyl]Tetrahydropyran-4-Carbohydroxamic Acid - Compound 2
Mono view Stereo pair view
Reference:
K.Murphy-Benenato,
N.B.Olivier,
A.Choy,
P.Ross,
M.Miller,
M.Hale.
Synthesis, Structure and Sar of Pyran-Based Lpxc Inhibitors Acs Med.Chem.Lett. 2014.
Page generated: Wed Dec 16 05:47:42 2020
ISSN: ISSN 1948-5875 DOI: 10.1021/ML500210X |
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