Zinc in PDB 4qoi: Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A

All present enzymatic activity of Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A:
1.10.99.2;

The structure of Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A, PDB code: 4qoi was solved by J.Serriere, J.A.Boutin, T.Isabet, M.Antoine, G.Ferry, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.69 / 1.55
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	56.240, 83.630, 106.830, 90.00, 90.00, 90.00
R / Rfree (%)	17.7 / 19.7

The binding sites of Zinc atom in the Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A (pdb code 4qoi). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A, PDB code: 4qoi:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:22.8 occ:1.00 ND1 A:HIS177 2.0 25.1 1.0 ND1 A:HIS173 2.0 24.3 1.0 O A:CYS222 2.1 22.1 1.0 SG A:CYS222 2.2 23.2 1.0 CB A:CYS222 2.8 20.4 1.0 C A:CYS222 2.9 25.2 1.0 CG A:HIS177 3.0 22.6 1.0 CE1 A:HIS173 3.0 23.4 1.0 CE1 A:HIS177 3.0 23.8 1.0 CG A:HIS173 3.1 22.7 1.0 CB A:HIS177 3.2 19.3 1.0 CA A:CYS222 3.4 20.6 1.0 CB A:HIS173 3.4 19.9 1.0 CA A:HIS173 3.6 18.9 1.0 N A:THR223 4.1 22.9 1.0 CD2 A:HIS177 4.1 24.0 1.0 NE2 A:HIS177 4.2 24.0 1.0 NE2 A:HIS173 4.2 23.7 1.0 CD2 A:HIS173 4.2 23.4 1.0 N A:HIS173 4.5 18.5 1.0 N A:CYS222 4.6 22.2 1.0 C A:HIS173 4.6 20.0 1.0 O A:HIS173 4.6 19.9 1.0 O A:GLN172 4.6 19.3 1.0 CA A:THR223 4.6 22.5 1.0 CA A:HIS177 4.8 18.4 1.0 C A:GLN172 4.9 18.9 1.0 CZ3 A:TRP169 5.0 25.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn302 b:33.7 occ:1.00 O B:CYS222 2.1 37.5 1.0 ND1 B:HIS173 2.1 34.6 1.0 ND1 B:HIS177 2.1 39.4 1.0 SG B:CYS222 2.2 37.9 1.0 CB B:CYS222 2.7 35.8 1.0 C B:CYS222 2.8 41.3 1.0 CE1 B:HIS173 3.1 34.8 1.0 CG B:HIS177 3.1 35.4 1.0 CG B:HIS173 3.1 32.8 1.0 CE1 B:HIS177 3.1 39.6 1.0 CA B:CYS222 3.3 37.4 1.0 CB B:HIS177 3.4 30.2 1.0 CB B:HIS173 3.4 28.3 1.0 CA B:HIS173 3.7 26.5 1.0 N B:THR223 3.9 39.5 1.0 NE2 B:HIS173 4.2 34.4 1.0 CD2 B:HIS173 4.3 33.2 1.0 NE2 B:HIS177 4.3 40.2 1.0 CD2 B:HIS177 4.3 39.1 1.0 N B:CYS222 4.5 40.1 1.0 CA B:THR223 4.5 39.8 1.0 N B:HIS173 4.5 25.5 1.0 O B:GLN172 4.7 30.3 1.0 C B:HIS173 4.7 28.2 1.0 O B:HIS173 4.7 28.0 1.0 C B:GLN172 4.9 29.7 1.0 CE1 B:HIS227 4.9 36.4 1.0 CA B:HIS177 4.9 28.0 1.0 CZ3 B:TRP169 4.9 35.0 1.0

J.Serriere, J.A.Boutin, T.Isabet, M.Antoine, G.Ferry. Crystal Structure of Fmn Quinone Reductase 2 in Complex with Melatonin at 1.55A To Be Published.