Zinc in PDB 4qog: Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A

All present enzymatic activity of Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A:
1.10.99.2;

The structure of Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A, PDB code: 4qog was solved by J.Serriere, J.A.Boutin, T.Isabet, M.Antoine, G.Ferry, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.81 / 1.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	56.560, 83.400, 106.860, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 22.5

The binding sites of Zinc atom in the Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A (pdb code 4qog). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A, PDB code: 4qog:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:15.6 occ:1.00 O A:CYS222 2.0 13.3 1.0 ND1 A:HIS173 2.1 16.1 1.0 ND1 A:HIS177 2.1 20.4 1.0 SG A:CYS222 2.3 15.2 1.0 CB A:CYS222 2.8 14.6 1.0 C A:CYS222 2.9 15.0 1.0 CE1 A:HIS173 3.0 16.5 1.0 CG A:HIS173 3.1 13.5 1.0 CG A:HIS177 3.1 15.0 1.0 CE1 A:HIS177 3.1 14.8 1.0 CB A:HIS177 3.3 14.6 1.0 CA A:CYS222 3.4 16.5 1.0 CB A:HIS173 3.5 12.3 1.0 CA A:HIS173 3.6 12.4 1.0 N A:THR223 4.0 16.6 1.0 NE2 A:HIS173 4.1 15.0 1.0 CD2 A:HIS173 4.2 14.1 1.0 NE2 A:HIS177 4.2 16.4 1.0 CD2 A:HIS177 4.3 15.0 1.0 N A:HIS173 4.6 12.4 1.0 CA A:THR223 4.6 16.7 1.0 N A:CYS222 4.6 18.2 1.0 C A:HIS173 4.6 13.6 1.0 O A:HIS173 4.6 12.6 1.0 O A:GLN172 4.7 13.1 1.0 CA A:HIS177 4.8 13.9 1.0 C A:GLN172 4.9 11.1 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn303 b:25.0 occ:1.00 O B:CYS222 2.0 16.3 1.0 ND1 B:HIS173 2.1 21.8 1.0 ND1 B:HIS177 2.1 29.8 1.0 SG B:CYS222 2.3 24.1 1.0 C B:CYS222 2.7 18.8 1.0 CB B:CYS222 2.8 21.3 1.0 CE1 B:HIS173 2.9 23.6 1.0 CG B:HIS177 3.0 24.5 1.0 CE1 B:HIS177 3.1 27.6 1.0 CG B:HIS173 3.1 19.7 1.0 CB B:HIS177 3.3 23.2 1.0 CA B:CYS222 3.3 27.5 1.0 CB B:HIS173 3.5 17.4 1.0 CA B:HIS173 3.7 17.7 1.0 N B:THR223 3.9 27.9 1.0 NE2 B:HIS173 4.1 23.0 1.0 CD2 B:HIS173 4.2 18.7 1.0 CD2 B:HIS177 4.2 25.4 1.0 NE2 B:HIS177 4.2 25.4 1.0 N B:CYS222 4.6 26.1 1.0 CA B:THR223 4.6 26.1 1.0 C B:HIS173 4.6 15.8 1.0 O B:HIS173 4.6 19.6 1.0 N B:HIS173 4.7 17.3 1.0 O B:GLN172 4.7 18.7 1.0 CA B:HIS177 4.7 21.5 1.0 CD1 B:TYR132 4.8 25.9 0.5 CE1 B:TYR132 4.8 24.1 0.5 CE1 B:HIS227 4.9 22.6 1.0 O B:HOH528 4.9 37.5 1.0 C B:GLN172 5.0 17.4 1.0

J.Serriere, J.A.Boutin, T.Isabet, M.Antoine, G.Ferry. Crystal Structure of Fad Quinone Reductase 2 in Complex with Melatonin at 1.4A To Be Published.