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Atomistry » Zinc » PDB 4q8v-4qhj » 4qa0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4q8v-4qhj » 4qa0 » |
Zinc in PDB 4qa0: Crystal Structure of C153F HDAC8 in Complex with SahaEnzymatic activity of Crystal Structure of C153F HDAC8 in Complex with Saha
All present enzymatic activity of Crystal Structure of C153F HDAC8 in Complex with Saha:
3.5.1.98; Protein crystallography data
The structure of Crystal Structure of C153F HDAC8 in Complex with Saha, PDB code: 4qa0
was solved by
C.Decroos,
C.B.Bowman,
J.-A.S.Moser,
K.E.Christianson,
M.A.Deardorff,
D.W.Christianson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4qa0:
The structure of Crystal Structure of C153F HDAC8 in Complex with Saha also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of C153F HDAC8 in Complex with Saha
(pdb code 4qa0). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of C153F HDAC8 in Complex with Saha, PDB code: 4qa0: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4qa0Go back to Zinc Binding Sites List in 4qa0
Zinc binding site 1 out
of 2 in the Crystal Structure of C153F HDAC8 in Complex with Saha
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4qa0Go back to Zinc Binding Sites List in 4qa0
Zinc binding site 2 out
of 2 in the Crystal Structure of C153F HDAC8 in Complex with Saha
Mono view Stereo pair view
Reference:
C.Decroos,
C.M.Bowman,
J.A.Moser,
K.E.Christianson,
M.A.Deardorff,
D.W.Christianson.
Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia De Lange Syndrome Spectrum Disorders. Acs Chem.Biol. V. 9 2157 2014.
Page generated: Wed Dec 16 05:43:05 2020
ISSN: ISSN 1554-8929 PubMed: 25075551 DOI: 10.1021/CB5003762 |
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