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Atomistry » Zinc » PDB 4p9d-4pof » 4pes » |
Zinc in PDB 4pes: Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]CarbamateEnzymatic activity of Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]Carbamate
All present enzymatic activity of Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]Carbamate:
3.4.24.56; Protein crystallography data
The structure of Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]Carbamate, PDB code: 4pes
was solved by
Y.Wang,
S.Guo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4pes:
The structure of Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]Carbamate also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]Carbamate
(pdb code 4pes). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]Carbamate, PDB code: 4pes: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4pesGo back to Zinc Binding Sites List in 4pes
Zinc binding site 1 out
of 2 in the Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]Carbamate
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4pesGo back to Zinc Binding Sites List in 4pes
Zinc binding site 2 out
of 2 in the Crystal Structure of Insulin Degrading Enzyme Complexed with Inhibitor Tert-Butyl [(2S)-2-(2,5-Difluorophenyl)-3-(Quinolin-3-Yl) Propyl]Carbamate
Mono view Stereo pair view
Reference:
T.B.Durham,
J.L.Toth,
V.J.Klimkowski,
J.X.C.Cao,
A.M.Siesky,
J.Alexander-Chacko,
G.Y.Wu,
J.T.Dixon,
J.E.Mcgee,
Y.Wang,
S.Guo,
R.N.Cavitt,
J.Schindler,
S.J.Thibodeaux,
N.A.Calvert,
M.J.Coghlan,
D.K.Sindelar,
M.Christe,
V.V.Kiselyov,
M.Dodson,
K.W.Sloop.
Crystal Structure of Ide Complexed with An Inhibitor To Be Published.
Page generated: Sun Oct 27 05:51:23 2024
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