Atomistry » Zinc » PDB 4o8x-4ojv » 4oip
Atomistry »
  Zinc »
    PDB 4o8x-4ojv »
      4oip »

Zinc in PDB 4oip: Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp

Enzymatic activity of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp

All present enzymatic activity of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp:
2.7.7.6;

Protein crystallography data

The structure of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp, PDB code: 4oip was solved by Y.Zhang, R.H.Ebright, E.Arnold, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.12 / 3.40
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 182.920, 104.391, 294.211, 90.00, 98.97, 90.00
R / Rfree (%) 20.8 / 24.6

Other elements in 4oip:

The structure of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp also contains other interesting chemical elements:

Magnesium (Mg) 6 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp (pdb code 4oip). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp, PDB code: 4oip:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4oip

Go back to Zinc Binding Sites List in 4oip
Zinc binding site 1 out of 2 in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2001

b:38.1
occ:1.00
SG D:CYS1201 2.3 31.7 1.0
SG D:CYS1112 2.3 34.4 1.0
SG D:CYS1194 2.3 26.9 1.0
SG D:CYS1204 2.3 36.2 1.0
CB D:CYS1204 3.1 35.9 1.0
CB D:CYS1194 3.2 33.3 1.0
CB D:CYS1201 3.4 32.0 1.0
CB D:CYS1112 3.5 32.5 1.0
CA D:CYS1194 3.6 31.7 1.0
OG1 D:THR1196 3.8 40.4 1.0
N D:CYS1201 3.9 33.4 1.0
N D:GLN1195 4.1 31.9 1.0
N D:CYS1112 4.2 42.7 1.0
CA D:CYS1201 4.2 33.4 1.0
C D:CYS1194 4.3 32.6 1.0
CG2 D:THR1114 4.3 37.4 1.0
CA D:CYS1204 4.4 38.1 1.0
N D:CYS1204 4.4 36.9 1.0
CA D:CYS1112 4.5 40.6 1.0
N D:THR1196 4.7 27.0 1.0
NH2 D:ARG1189 4.7 43.5 1.0
N D:CYS1194 4.8 31.6 1.0
OD1 D:ASP1111 4.8 42.4 1.0
CB D:THR1196 4.9 32.8 1.0
C D:CYS1201 4.9 35.1 1.0

Zinc binding site 2 out of 2 in 4oip

Go back to Zinc Binding Sites List in 4oip
Zinc binding site 2 out of 2 in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077, Atp, and Cmpcpp within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2002

b:79.9
occ:1.00
SG D:CYS76 2.3 54.4 1.0
SG D:CYS60 2.3 75.0 1.0
SG D:CYS73 2.3 84.1 1.0
SG D:CYS58 2.3 87.9 1.0
CB D:CYS58 3.0 76.0 1.0
CB D:CYS73 3.1 70.8 1.0
CB D:CYS76 3.6 57.9 1.0
CB D:LYS62 3.7 91.4 1.0
N D:CYS60 3.8 77.9 1.0
CB D:CYS60 3.8 72.2 1.0
N D:LYS62 3.8 88.2 1.0
N D:GLY61 4.0 81.5 1.0
N D:ALA59 4.2 55.6 1.0
N D:CYS76 4.2 80.7 1.0
CA D:CYS60 4.2 71.9 1.0
CA D:CYS58 4.3 61.6 1.0
CA D:LYS62 4.4 92.0 1.0
C D:CYS58 4.4 57.9 1.0
C D:CYS60 4.4 78.4 1.0
CA D:CYS76 4.5 68.7 1.0
CA D:CYS73 4.6 71.4 1.0
CD2 D:TYR63 4.7 93.9 1.0
C D:ALA59 4.8 73.0 1.0
C D:GLY61 4.8 86.2 1.0
N D:TYR63 4.8 87.3 1.0
CA D:GLY61 4.9 83.4 1.0
CE2 D:TYR63 5.0 92.0 1.0
CA D:ALA59 5.0 58.4 1.0
CB D:ARG75 5.0 77.0 1.0
CG D:LYS62 5.0 88.4 1.0

Reference:

Y.Zhang, D.Degen, M.X.Ho, E.Sineva, K.Y.Ebright, Y.W.Ebright, V.Mekler, H.Vahedian-Movahed, Y.Feng, R.Yin, S.Tuske, H.Irschik, R.Jansen, S.Maffioli, S.Donadio, E.Arnold, R.H.Ebright. GE23077 Binds to the Rna Polymerase 'I' and 'I+1' Sites and Prevents the Binding of Initiating Nucleotides. Elife V. 3 02450 2014.
ISSN: ESSN 2050-084X
PubMed: 24755292
Page generated: Sun Oct 27 03:45:48 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy