Zinc in PDB 4ocl: Crystal Structure of the RPN8-RPN11 Mpn Domain Heterodimer, Crystal Form Ia

The structure of Crystal Structure of the RPN8-RPN11 Mpn Domain Heterodimer, Crystal Form Ia, PDB code: 4ocl was solved by G.R.Pathare, A.Bracher, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.40
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	45.258, 63.431, 100.111, 100.08, 92.75, 90.62
R / Rfree (%)	19.5 / 25.2

The binding sites of Zinc atom in the Crystal Structure of the RPN8-RPN11 Mpn Domain Heterodimer, Crystal Form Ia (pdb code 4ocl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the RPN8-RPN11 Mpn Domain Heterodimer, Crystal Form Ia, PDB code: 4ocl:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the RPN8-RPN11 Mpn Domain Heterodimer, Crystal Form Ia


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the RPN8-RPN11 Mpn Domain Heterodimer, Crystal Form Ia within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:74.9 occ:1.00 NE2 B:HIS109 2.2 46.1 1.0 OD2 B:ASP122 2.3 55.3 1.0 ND1 B:HIS111 2.6 58.9 1.0 CG B:ASP122 2.8 47.5 1.0 OD1 B:ASP122 2.8 48.5 1.0 CE1 B:HIS111 3.0 58.5 1.0 CE1 B:HIS109 3.1 40.6 1.0 CD2 B:HIS109 3.2 40.4 1.0 OE1 B:GLU48 3.4 57.5 1.0 CG B:HIS111 3.9 57.6 1.0 OG B:SER119 4.1 56.1 1.0 CB B:ASP122 4.1 43.8 1.0 ND1 B:HIS109 4.2 40.1 1.0 NE2 B:HIS111 4.3 60.9 1.0 CG B:HIS109 4.3 37.1 1.0 N B:SER119 4.4 54.5 1.0 CD B:GLU48 4.6 56.7 1.0 O B:TRP117 4.6 53.4 1.0 CB B:HIS111 4.6 55.7 1.0 CB B:SER119 4.7 57.9 1.0 CD2 B:HIS111 4.7 58.3 1.0 CA B:LEU118 5.0 53.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the RPN8-RPN11 Mpn Domain Heterodimer, Crystal Form Ia


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the RPN8-RPN11 Mpn Domain Heterodimer, Crystal Form Ia within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn401 b:64.9 occ:1.00 NE2 E:HIS111 1.9 42.6 1.0 OD2 E:ASP122 2.2 47.6 1.0 NE2 E:HIS109 2.2 34.1 1.0 O E:HOH508 2.5 48.8 1.0 CG E:ASP122 2.9 41.0 1.0 CD2 E:HIS111 2.9 40.8 1.0 CE1 E:HIS111 2.9 42.5 1.0 OD1 E:ASP122 2.9 41.7 1.0 CE1 E:HIS109 3.1 30.1 1.0 CD2 E:HIS109 3.2 32.0 1.0 OG E:SER119 3.4 48.3 1.0 ND1 E:HIS111 4.0 46.5 1.0 CG E:HIS111 4.0 44.5 1.0 N E:SER119 4.3 43.4 1.0 ND1 E:HIS109 4.3 30.7 1.0 CB E:ASP122 4.3 36.4 1.0 CG E:HIS109 4.3 30.6 1.0 O E:TRP117 4.5 43.3 1.0 CB E:SER119 4.5 47.0 1.0

G.R.Pathare, I.Nagy, P.Sledz, D.J.Anderson, H.J.Zhou, E.Pardon, J.Steyaert, F.Forster, A.Bracher, W.Baumeister. Crystal Structure of the Proteasomal Deubiquitylation Module RPN8-RPN11. Proc.Natl.Acad.Sci.Usa V. 111 2984 2014.
ISSN: ISSN 0027-8424
PubMed: 24516147
DOI: 10.1073/PNAS.1400546111