Zinc in PDB 4kxc: Crystal Structure of Human Aminopeptidase A Complexed with Glutamate

Enzymatic activity of Crystal Structure of Human Aminopeptidase A Complexed with Glutamate

All present enzymatic activity of Crystal Structure of Human Aminopeptidase A Complexed with Glutamate:
3.4.11.7;

Protein crystallography data

The structure of Crystal Structure of Human Aminopeptidase A Complexed with Glutamate, PDB code: 4kxc was solved by Y.Yang, C.Liu, Y.Y.Lin, F.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.81 / 2.40
Space group P 64 2 2
Cell size a, b, c (Å), α, β, γ (°) 142.155, 142.155, 237.066, 90.00, 90.00, 120.00
R / Rfree (%) 16.7 / 22.6

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human Aminopeptidase A Complexed with Glutamate (pdb code 4kxc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Aminopeptidase A Complexed with Glutamate, PDB code: 4kxc:

Zinc binding site 1 out of 1 in 4kxc

Go back to Zinc Binding Sites List in 4kxc
Zinc binding site 1 out of 1 in the Crystal Structure of Human Aminopeptidase A Complexed with Glutamate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Aminopeptidase A Complexed with Glutamate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1001

b:74.1
occ:1.00
OE1 A:GLU416 2.0 58.1 1.0
NE2 A:HIS397 2.1 58.8 1.0
NE2 A:HIS393 2.1 48.3 1.0
O A:HOH1225 2.7 71.0 1.0
CD A:GLU416 2.9 59.0 1.0
CD2 A:HIS393 2.9 50.4 1.0
CD2 A:HIS397 3.0 57.9 1.0
OE2 A:GLU416 3.1 62.5 1.0
N A:GLU1019 3.1 70.2 1.0
CE1 A:HIS397 3.2 58.9 1.0
CE1 A:HIS393 3.2 49.6 1.0
OXT A:GLU1019 3.8 90.6 1.0
C A:GLU1019 3.8 93.4 1.0
OH A:TYR479 4.0 57.6 1.0
CE2 A:TYR479 4.0 45.6 1.0
CA A:GLU1019 4.0 77.2 1.0
CG A:HIS393 4.1 49.2 1.0
CB A:ALA419 4.2 51.8 1.0
CG A:HIS397 4.2 57.6 1.0
O A:GLU1019 4.2 94.5 1.0
ND1 A:HIS397 4.2 58.9 1.0
ND1 A:HIS393 4.2 52.1 1.0
CG A:GLU416 4.3 59.7 1.0
CZ A:TYR479 4.3 49.7 1.0
OE1 A:GLU360 4.5 63.8 1.0
CA A:GLU416 4.6 53.3 1.0
CB A:GLU416 4.7 55.1 1.0
OE2 A:GLU360 4.7 60.6 1.0
OE2 A:GLU394 4.8 57.1 1.0
CD A:GLU360 4.9 58.6 1.0
O A:HOH1295 4.9 57.8 1.0

Reference:

Y.Yang, C.Liu, Y.L.Lin, F.Li. Structural Insights Into Central Hypertension Regulation By Human Aminopeptidase A. J.Biol.Chem. V. 288 25638 2013.
ISSN: ISSN 0021-9258
PubMed: 23888046
DOI: 10.1074/JBC.M113.494955
Page generated: Wed Dec 16 05:30:14 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy