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Atomistry » Zinc » PDB 4kjm-4kxc » 4knj » |
Zinc in PDB 4knj: Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-4-[(Pyrimidin-2-Ylsulfanyl)Acetyl]BenzenesulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-4-[(Pyrimidin-2-Ylsulfanyl)Acetyl]Benzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-4-[(Pyrimidin-2-Ylsulfanyl)Acetyl]Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-4-[(Pyrimidin-2-Ylsulfanyl)Acetyl]Benzenesulfonamide, PDB code: 4knj
was solved by
A.Smirnov,
E.Manakova,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4knj:
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-4-[(Pyrimidin-2-Ylsulfanyl)Acetyl]Benzenesulfonamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-4-[(Pyrimidin-2-Ylsulfanyl)Acetyl]Benzenesulfonamide
(pdb code 4knj). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-4-[(Pyrimidin-2-Ylsulfanyl)Acetyl]Benzenesulfonamide, PDB code: 4knj: Zinc binding site 1 out of 1 in 4knjGo back to Zinc Binding Sites List in 4knj
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-4-[(Pyrimidin-2-Ylsulfanyl)Acetyl]Benzenesulfonamide
Mono view Stereo pair view
Reference:
E.Capkauskaite,
A.Zubriene,
A.Smirnov,
J.Torresan,
M.Kisonaite,
J.Kazokaite,
J.Gylyte,
V.Michailoviene,
V.Jogaite,
E.Manakova,
S.Grazulis,
S.Tumkevicius,
D.Matulis.
Benzenesulfonamides with Pyrimidine Moiety As Inhibitors of Human Carbonic Anhydrases I, II, VI, VII, XII, and XIII Bioorg.Med.Chem. V. 21 6937 2013.
Page generated: Wed Dec 16 05:29:34 2020
ISSN: ISSN 0968-0896 PubMed: 24103428 DOI: 10.1016/J.BMC.2013.09.029 |
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