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Atomistry » Zinc » PDB 4k99-4kjg » 4kcn » |
Zinc in PDB 4kcn: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with N-(3-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)Thiophene-2- CarboximidamideEnzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with N-(3-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)Thiophene-2- Carboximidamide
All present enzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with N-(3-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)Thiophene-2- Carboximidamide:
1.14.13.39; Protein crystallography data
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with N-(3-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)Thiophene-2- Carboximidamide, PDB code: 4kcn
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4kcn:
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with N-(3-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)Thiophene-2- Carboximidamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with N-(3-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)Thiophene-2- Carboximidamide
(pdb code 4kcn). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with N-(3-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)Thiophene-2- Carboximidamide, PDB code: 4kcn: Zinc binding site 1 out of 1 in 4kcnGo back to Zinc Binding Sites List in 4kcn
Zinc binding site 1 out
of 1 in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with N-(3-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)Thiophene-2- Carboximidamide
Mono view Stereo pair view
Reference:
H.Huang,
H.Li,
S.Yang,
G.Chreifi,
P.Martasek,
L.J.Roman,
F.L.Meyskens,
T.L.Poulos,
R.B.Silverman.
Potent and Selective Double-Headed Thiophene-2-Carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase For the Treatment of Melanoma. J.Med.Chem. V. 57 686 2014.
Page generated: Sun Oct 27 01:08:04 2024
ISSN: ISSN 0022-2623 PubMed: 24447275 DOI: 10.1021/JM401252E |
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