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Atomistry » Zinc » PDB 4k4f-4k98 » 4k5z » |
Zinc in PDB 4k5z: Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-Chloro-2,3-Dihydro-1H-Isoindol-1-OneEnzymatic activity of Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-Chloro-2,3-Dihydro-1H-Isoindol-1-One
All present enzymatic activity of Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-Chloro-2,3-Dihydro-1H-Isoindol-1-One:
3.4.21.39; Protein crystallography data
The structure of Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-Chloro-2,3-Dihydro-1H-Isoindol-1-One, PDB code: 4k5z
was solved by
B.K.Collins,
A.K.Padyana,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4k5z:
The structure of Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-Chloro-2,3-Dihydro-1H-Isoindol-1-One also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-Chloro-2,3-Dihydro-1H-Isoindol-1-One
(pdb code 4k5z). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-Chloro-2,3-Dihydro-1H-Isoindol-1-One, PDB code: 4k5z: Zinc binding site 1 out of 1 in 4k5zGo back to Zinc Binding Sites List in 4k5z
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-Chloro-2,3-Dihydro-1H-Isoindol-1-One
Mono view Stereo pair view
Reference:
S.J.Taylor,
A.K.Padyana,
A.Abeywardane,
S.Liang,
M.H.Hao,
S.De Lombaert,
J.Proudfoot,
B.S.Farmer,
X.Li,
B.Collins,
L.Martin,
D.R.Albaugh,
M.Hill-Drzewi,
S.S.Pullen,
H.Takahashi.
Discovery of Potent, Selective Chymase Inhibitors Via Fragment Linking Strategies. J.Med.Chem. V. 56 4465 2013.
Page generated: Sun Oct 27 01:45:03 2024
ISSN: ISSN 0022-2623 PubMed: 23659209 DOI: 10.1021/JM400138Z |
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