Zinc in PDB 4fdg: Crystal Structure of An Archaeal Mcm Filament

All present enzymatic activity of Crystal Structure of An Archaeal Mcm Filament:
3.6.4.12;

The structure of Crystal Structure of An Archaeal Mcm Filament, PDB code: 4fdg was solved by I.M.Slaymaker, Y.Fu, A.B.Brewster, X.S.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.58 / 4.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	169.663, 107.737, 170.205, 90.00, 107.89, 90.00
R / Rfree (%)	33.1 / 34.1

The binding sites of Zinc atom in the Crystal Structure of An Archaeal Mcm Filament (pdb code 4fdg). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 5 binding sites of Zinc where determined in the Crystal Structure of An Archaeal Mcm Filament, PDB code: 4fdg:
Jump to Zinc binding site number: 1; 2; 3; 4; 5;

Zinc binding site 1 out of 5 in the Crystal Structure of An Archaeal Mcm Filament


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of An Archaeal Mcm Filament within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn701 b:0.9 occ:1.00 SG B:CYS174 2.0 0.8 1.0 ND1 B:HIS144 2.2 0.7 1.0 SG B:CYS171 2.2 0.7 1.0 SG B:CYS149 2.3 0.8 1.0 CE1 B:HIS144 3.0 0.8 1.0 CG B:HIS144 3.3 0.8 1.0 CB B:CYS174 3.3 0.0 1.0 CB B:CYS171 3.5 0.5 1.0 N B:CYS174 3.5 0.0 1.0 O B:LYS176 3.7 0.4 1.0 CB B:CYS149 3.7 0.1 1.0 CB B:HIS144 3.8 0.2 1.0 N B:GLY175 4.0 1.0 1.0 CA B:CYS174 4.0 0.0 1.0 O B:CYS171 4.1 0.7 1.0 O B:ASP148 4.1 0.8 1.0 NE2 B:HIS144 4.2 0.1 1.0 N B:LYS176 4.2 0.7 1.0 CD2 B:HIS144 4.3 0.7 1.0 C B:CYS171 4.4 0.2 1.0 CB B:LYS173 4.4 0.9 1.0 CA B:CYS171 4.4 0.1 1.0 C B:CYS174 4.5 0.0 1.0 CZ B:PHE180 4.5 0.1 1.0 C B:LYS176 4.6 0.3 1.0 C B:LYS173 4.6 0.3 1.0 N B:CYS171 4.7 1.0 1.0 N B:LYS173 4.8 0.1 1.0 CE1 B:PHE180 4.8 0.7 1.0 CA B:CYS149 4.8 0.1 1.0 CA B:LYS173 4.8 0.2 1.0 CA B:LYS176 4.9 0.6 1.0 CA B:GLY175 5.0 0.9 1.0

Zinc binding site 2 out of 5 in the Crystal Structure of An Archaeal Mcm Filament


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of An Archaeal Mcm Filament within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:0.8 occ:1.00 SG A:CYS174 2.0 0.3 1.0 SG A:CYS171 2.2 0.1 1.0 ND1 A:HIS144 2.2 0.6 1.0 SG A:CYS149 2.3 0.9 1.0 CE1 A:HIS144 3.0 0.3 1.0 CG A:HIS144 3.3 0.7 1.0 CB A:CYS174 3.4 1.0 1.0 CB A:CYS171 3.5 0.5 1.0 N A:CYS174 3.5 0.8 1.0 O A:LYS176 3.7 0.4 1.0 CB A:CYS149 3.7 0.6 1.0 CB A:HIS144 3.7 0.6 1.0 CA A:CYS174 4.0 0.2 1.0 N A:GLY175 4.0 0.6 1.0 O A:CYS171 4.1 0.5 1.0 O A:ASP148 4.2 0.6 1.0 NE2 A:HIS144 4.2 0.6 1.0 N A:LYS176 4.2 0.6 1.0 CD2 A:HIS144 4.4 0.1 1.0 CB A:LYS173 4.4 0.9 1.0 C A:CYS171 4.4 0.8 1.0 CA A:CYS171 4.4 0.5 1.0 C A:CYS174 4.5 0.0 1.0 CZ A:PHE180 4.5 0.0 1.0 C A:LYS173 4.6 0.1 1.0 C A:LYS176 4.7 0.5 1.0 N A:CYS171 4.7 0.3 1.0 N A:LYS173 4.7 0.1 1.0 CE1 A:PHE180 4.8 0.2 1.0 CA A:CYS149 4.8 0.1 1.0 CA A:LYS173 4.8 0.4 1.0 CA A:LYS176 5.0 0.6 1.0

Zinc binding site 3 out of 5 in the Crystal Structure of An Archaeal Mcm Filament


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of An Archaeal Mcm Filament within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn701 b:0.6 occ:1.00 SG C:CYS174 2.0 0.8 1.0 SG C:CYS171 2.1 0.8 1.0 ND1 C:HIS144 2.2 0.3 1.0 SG C:CYS149 2.3 0.8 1.0 CE1 C:HIS144 3.0 0.9 1.0 CG C:HIS144 3.3 0.7 1.0 CB C:CYS174 3.4 0.3 1.0 CB C:CYS171 3.5 0.7 1.0 N C:CYS174 3.5 0.6 1.0 O C:LYS176 3.7 0.4 1.0 CB C:CYS149 3.7 0.3 1.0 CB C:HIS144 3.8 0.1 1.0 CA C:CYS174 3.9 0.2 1.0 N C:GLY175 4.0 0.8 1.0 O C:CYS171 4.1 0.2 1.0 O C:ASP148 4.2 0.1 1.0 NE2 C:HIS144 4.2 0.2 1.0 N C:LYS176 4.2 0.6 1.0 CB C:LYS173 4.4 0.8 1.0 CD2 C:HIS144 4.4 0.5 1.0 C C:CYS171 4.4 0.1 1.0 CA C:CYS171 4.4 0.8 1.0 C C:CYS174 4.5 0.4 1.0 CZ C:PHE180 4.5 0.8 1.0 C C:LYS173 4.6 0.4 1.0 C C:LYS176 4.7 0.6 1.0 N C:CYS171 4.7 0.4 1.0 N C:LYS173 4.7 0.0 1.0 CE1 C:PHE180 4.8 0.4 1.0 CA C:LYS173 4.8 0.4 1.0 CA C:CYS149 4.8 0.6 1.0 CA C:LYS176 5.0 0.6 1.0

Zinc binding site 4 out of 5 in the Crystal Structure of An Archaeal Mcm Filament


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of An Archaeal Mcm Filament within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn701 b:0.1 occ:1.00 SG D:CYS174 2.0 0.5 1.0 ND1 D:HIS144 2.2 0.4 1.0 SG D:CYS171 2.2 0.7 1.0 SG D:CYS149 2.3 0.3 1.0 CE1 D:HIS144 3.0 0.6 1.0 CG D:HIS144 3.3 0.9 1.0 CB D:CYS174 3.3 0.0 1.0 N D:CYS174 3.5 0.0 1.0 CB D:CYS171 3.5 0.9 1.0 CB D:CYS149 3.7 0.6 1.0 CB D:HIS144 3.7 0.1 1.0 O D:LYS176 3.7 0.4 1.0 CA D:CYS174 3.9 0.0 1.0 N D:GLY175 4.0 1.0 1.0 O D:ASP148 4.1 0.2 1.0 O D:CYS171 4.2 0.7 1.0 NE2 D:HIS144 4.2 0.5 1.0 N D:LYS176 4.3 0.6 1.0 CD2 D:HIS144 4.3 0.7 1.0 CB D:LYS173 4.4 0.1 1.0 C D:CYS171 4.5 0.7 1.0 CA D:CYS171 4.5 0.7 1.0 C D:CYS174 4.5 0.0 1.0 CZ D:PHE180 4.5 0.8 1.0 C D:LYS173 4.6 0.8 1.0 C D:LYS176 4.7 0.9 1.0 CA D:CYS149 4.7 0.5 1.0 N D:LYS173 4.7 0.4 1.0 N D:CYS171 4.8 0.8 1.0 CE1 D:PHE180 4.8 0.7 1.0 CA D:LYS173 4.8 0.7 1.0 CA D:LYS176 5.0 0.6 1.0

Zinc binding site 5 out of 5 in the Crystal Structure of An Archaeal Mcm Filament


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Structure of An Archaeal Mcm Filament within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn701 b:1.0 occ:1.00 SG E:CYS174 2.0 0.9 1.0 SG E:CYS171 2.2 0.3 1.0 ND1 E:HIS144 2.2 0.0 1.0 SG E:CYS149 2.3 0.4 1.0 CE1 E:HIS144 3.0 0.3 1.0 CG E:HIS144 3.3 0.5 1.0 CB E:CYS174 3.3 0.0 1.0 CB E:CYS171 3.5 0.4 1.0 N E:CYS174 3.5 0.0 1.0 O E:LYS176 3.7 0.4 1.0 CB E:CYS149 3.7 0.9 1.0 CB E:HIS144 3.8 0.2 1.0 CA E:CYS174 3.9 0.0 1.0 N E:GLY175 4.0 1.0 1.0 O E:CYS171 4.1 0.8 1.0 O E:ASP148 4.1 0.8 1.0 NE2 E:HIS144 4.2 0.0 1.0 N E:LYS176 4.2 0.1 1.0 CD2 E:HIS144 4.4 0.2 1.0 CB E:LYS173 4.4 0.8 1.0 C E:CYS171 4.4 0.9 1.0 CA E:CYS171 4.4 0.9 1.0 C E:CYS174 4.5 0.0 1.0 CZ E:PHE180 4.5 0.4 1.0 C E:LYS173 4.6 0.3 1.0 C E:LYS176 4.7 0.8 1.0 N E:CYS171 4.7 0.0 1.0 N E:LYS173 4.7 0.2 1.0 CE1 E:PHE180 4.8 0.8 1.0 CA E:CYS149 4.8 0.7 1.0 CA E:LYS173 4.8 0.6 1.0 CA E:LYS176 5.0 0.6 1.0

I.M.Slaymaker, Y.Fu, D.B.Toso, N.Ranatunga, A.Brewster, S.L.Forsburg, Z.H.Zhou, X.S.Chen. Mini-Chromosome Maintenance Complexes Form A Filament to Remodel Dna Structure and Topology. Nucleic Acids Res. V. 41 3446 2013.
ISSN: ISSN 0305-1048
PubMed: 23361460
DOI: 10.1093/NAR/GKT022