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Atomistry » Zinc » PDB 4csh-4cxp » 4ctp » |
Zinc in PDB 4ctp: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with (S)-6-(2-Amino-2-(3-(2-(6-Amino-4- Methylpyridin-2-Yl)Ethyl)Phenyl)Ethyl)-4-Methylpyridin-2- AmineEnzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with (S)-6-(2-Amino-2-(3-(2-(6-Amino-4- Methylpyridin-2-Yl)Ethyl)Phenyl)Ethyl)-4-Methylpyridin-2- Amine
All present enzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with (S)-6-(2-Amino-2-(3-(2-(6-Amino-4- Methylpyridin-2-Yl)Ethyl)Phenyl)Ethyl)-4-Methylpyridin-2- Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with (S)-6-(2-Amino-2-(3-(2-(6-Amino-4- Methylpyridin-2-Yl)Ethyl)Phenyl)Ethyl)-4-Methylpyridin-2- Amine, PDB code: 4ctp
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ctp:
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with (S)-6-(2-Amino-2-(3-(2-(6-Amino-4- Methylpyridin-2-Yl)Ethyl)Phenyl)Ethyl)-4-Methylpyridin-2- Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with (S)-6-(2-Amino-2-(3-(2-(6-Amino-4- Methylpyridin-2-Yl)Ethyl)Phenyl)Ethyl)-4-Methylpyridin-2- Amine
(pdb code 4ctp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with (S)-6-(2-Amino-2-(3-(2-(6-Amino-4- Methylpyridin-2-Yl)Ethyl)Phenyl)Ethyl)-4-Methylpyridin-2- Amine, PDB code: 4ctp: Zinc binding site 1 out of 1 in 4ctpGo back to Zinc Binding Sites List in 4ctp
Zinc binding site 1 out
of 1 in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with (S)-6-(2-Amino-2-(3-(2-(6-Amino-4- Methylpyridin-2-Yl)Ethyl)Phenyl)Ethyl)-4-Methylpyridin-2- Amine
Mono view Stereo pair view
Reference:
S.Kang,
W.Tang,
H.Li,
G.Chreifi,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Nitric Oxide Synthase Inhibitors That Interact with Both A Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity. J.Med.Chem. V. 57 4382 2014.
Page generated: Sat Oct 26 21:04:01 2024
ISSN: ISSN 0022-2623 PubMed: 24758147 DOI: 10.1021/JM5004182 |
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