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Zinc in PDB 4cqd: The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies

Enzymatic activity of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies

All present enzymatic activity of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies:
3.5.99.4;

Protein crystallography data

The structure of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies, PDB code: 4cqd was solved by S.Balotra, J.Newman, N.G.French, T.S.Peat, C.Scott, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 43.57 / 2.25
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 106.346, 87.063, 113.859, 90.00, 104.58, 90.00
R / Rfree (%) 16.626 / 19.434

Other elements in 4cqd:

The structure of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies (pdb code 4cqd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies, PDB code: 4cqd:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4cqd

Go back to Zinc Binding Sites List in 4cqd
Zinc binding site 1 out of 2 in the The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1404

b:25.7
occ:1.00
 NE2 A:HIS60 2.1 20.7 1.0
NE2 A:HIS62 2.1 18.8 1.0
O A:HOH2009 2.2 28.0 1.0
NE2 A:HIS217 2.2 24.0 1.0
OD1 A:ASP303 2.5 21.9 1.0
CE1 A:HIS62 3.0 17.9 1.0
CE1 A:HIS60 3.0 22.1 1.0
CD2 A:HIS60 3.1 21.3 1.0
CD2 A:HIS217 3.1 22.9 1.0
CD2 A:HIS62 3.2 17.5 1.0
CE1 A:HIS217 3.2 22.8 1.0
CG A:ASP303 3.5 23.1 1.0
O7 A:MLI1407 3.6 27.7 1.0
OD2 A:ASP303 3.7 23.9 1.0
C2 A:MLI1407 3.9 28.5 1.0
ND1 A:HIS60 4.2 20.8 1.0
ND1 A:HIS62 4.2 17.3 1.0
CG A:HIS60 4.2 19.5 1.0
CG A:HIS217 4.2 22.9 1.0
ND1 A:HIS217 4.2 24.3 1.0
CG A:HIS62 4.3 17.6 1.0
O6 A:MLI1407 4.4 25.7 1.0
O9 A:MLI1407 4.4 34.7 1.0
OD1 A:ASN304 4.4 20.7 1.0
C1 A:MLI1407 4.5 26.9 1.0
C3 A:MLI1407 4.6 30.8 1.0
NE2 A:HIS219 4.8 32.0 0.5
CB A:ASP303 4.8 19.7 1.0
CE1 A:HIS219 4.9 30.8 0.5

Zinc binding site 2 out of 2 in 4cqd

Go back to Zinc Binding Sites List in 4cqd
Zinc binding site 2 out of 2 in the The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1404

b:26.6
occ:1.00
 O B:HOH2013 2.1 25.1 1.0
NE2 B:HIS60 2.1 17.7 1.0
NE2 B:HIS62 2.1 16.6 1.0
NE2 B:HIS217 2.2 22.5 1.0
OD1 B:ASP303 2.5 23.1 1.0
CE1 B:HIS62 3.0 16.8 1.0
CE1 B:HIS60 3.1 18.8 1.0
CD2 B:HIS60 3.1 19.2 1.0
CD2 B:HIS217 3.1 23.7 1.0
CD2 B:HIS62 3.2 16.9 1.0
CE1 B:HIS217 3.2 22.4 1.0
CG B:ASP303 3.5 21.7 1.0
O9 B:MLI1407 3.6 26.0 1.0
OD2 B:ASP303 3.7 20.3 1.0
C3 B:MLI1407 4.0 27.0 1.0
ND1 B:HIS62 4.2 16.8 1.0
ND1 B:HIS60 4.2 20.3 1.0
CG B:HIS60 4.2 18.0 1.0
ND1 B:HIS217 4.2 24.3 1.0
CG B:HIS217 4.2 22.9 1.0
CG B:HIS62 4.3 17.3 1.0
C1 B:MLI1407 4.4 27.2 1.0
OD1 B:ASN304 4.4 18.0 1.0
O7 B:MLI1407 4.4 34.1 1.0
O8 B:MLI1407 4.5 22.0 1.0
C2 B:MLI1407 4.7 30.2 1.0
NE2 B:HIS219 4.7 30.8 0.5
CB B:ASP303 4.9 19.3 1.0
CE1 B:HIS219 5.0 30.0 0.5

Reference:

S.Balotra, J.Newman, N.G.French, T.S.Peat, C.Scott. The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies To Be Published.
Page generated: Sat Oct 26 20:58:48 2024

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