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Zinc in PDB 4cqc: The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies

Enzymatic activity of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies

All present enzymatic activity of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies:
3.5.99.4;

Protein crystallography data

The structure of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies, PDB code: 4cqc was solved by S.Balotra, J.Newman, N.G.French, T.S.Peat, C.Scott, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.37 / 2.20
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 106.234, 87.280, 114.364, 90.00, 103.93, 90.00
R / Rfree (%) 19.556 / 22.311

Other elements in 4cqc:

The structure of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies (pdb code 4cqc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies, PDB code: 4cqc:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4cqc

Go back to Zinc Binding Sites List in 4cqc
Zinc binding site 1 out of 2 in the The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1404

b:47.5
occ:1.00
 NE2 A:HIS62 2.2 27.0 1.0
NE2 A:HIS60 2.2 23.9 1.0
NE2 A:HIS217 2.6 36.1 1.0
OD1 A:ASP303 2.7 33.8 1.0
CE1 A:HIS62 3.1 25.3 1.0
CE1 A:HIS60 3.1 26.7 1.0
CD2 A:HIS62 3.2 26.6 1.0
CD2 A:HIS60 3.2 25.1 1.0
CD2 A:HIS217 3.3 34.2 1.0
CE1 A:HIS217 3.5 33.1 1.0
CG A:ASP303 3.7 32.6 1.0
NE2 A:HIS249 3.7 26.9 1.0
OD2 A:ASP303 3.9 32.9 1.0
O A:HOH2012 4.0 36.1 1.0
ND1 A:HIS60 4.2 26.8 1.0
ND1 A:HIS62 4.2 26.2 1.0
OD1 A:ASN304 4.3 28.8 1.0
CG A:HIS62 4.3 27.8 1.0
CG A:HIS60 4.3 22.3 1.0
CE1 A:HIS249 4.3 24.6 1.0
CG A:HIS217 4.4 31.2 1.0
ND1 A:HIS217 4.5 32.7 1.0
CD2 A:HIS249 4.7 24.7 1.0

Zinc binding site 2 out of 2 in 4cqc

Go back to Zinc Binding Sites List in 4cqc
Zinc binding site 2 out of 2 in the The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1404

b:46.2
occ:1.00
 NE2 B:HIS62 2.2 24.2 1.0
NE2 B:HIS60 2.2 20.5 1.0
NE2 B:HIS217 2.5 30.3 1.0
OD1 B:ASP303 2.7 33.7 1.0
CE1 B:HIS62 3.1 22.3 1.0
CE1 B:HIS60 3.2 20.9 1.0
CD2 B:HIS62 3.2 24.0 1.0
CD2 B:HIS60 3.2 20.3 1.0
CD2 B:HIS217 3.3 30.0 1.0
CE1 B:HIS217 3.5 28.3 1.0
CG B:ASP303 3.7 29.9 1.0
NE2 B:HIS249 3.7 23.3 1.0
OD2 B:ASP303 3.9 27.4 1.0
ND1 B:HIS62 4.2 23.2 1.0
OD1 B:ASN304 4.2 24.7 1.0
ND1 B:HIS60 4.3 21.7 1.0
CG B:HIS62 4.3 23.4 1.0
CG B:HIS60 4.3 19.1 1.0
CE1 B:HIS249 4.3 24.7 1.0
O B:HOH2015 4.3 34.9 1.0
CG B:HIS217 4.4 28.0 1.0
ND1 B:HIS217 4.5 30.3 1.0
CD2 B:HIS249 4.7 22.2 1.0

Reference:

S.Balotra, J.Newman, N.G.French, T.S.Peat, C.Scott. The Reaction Mechanism of the N-Isopropylammelide Isopropylaminohydrolase Atzc: Insights From Structural and Mutagenesis Studies To Be Published.
Page generated: Sat Oct 26 20:58:48 2024

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