Zinc in PDB 4cpa: Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution

All present enzymatic activity of Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution:
3.4.17.1;

The structure of Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution, PDB code: 4cpa was solved by W.N.Lipscomb, D.C.Rees, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 2.50
Space group	P 32
Cell size a, b, c (Å), α, β, γ (°)	53.450, 53.450, 218.500, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The binding sites of Zinc atom in the Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution (pdb code 4cpa). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution, PDB code: 4cpa:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ I:Zn308 b:10.6 occ:1.00 O I:VAL38 1.7 8.2 1.0 OE2 A:GLU72 2.0 18.3 1.0 ND1 A:HIS69 2.2 3.0 1.0 ND1 A:HIS196 2.3 3.0 1.0 CD A:GLU72 2.6 3.0 1.0 OE1 A:GLU72 2.6 19.5 1.0 C I:VAL38 2.7 10.5 1.0 CE1 A:HIS69 2.9 3.0 1.0 CE1 A:HIS196 3.0 3.0 1.0 OXT I:VAL38 3.2 20.4 1.0 CG A:HIS196 3.4 3.0 1.0 CG A:HIS69 3.4 3.0 1.0 CB A:HIS196 3.7 3.0 1.0 CB A:HIS69 3.9 3.0 1.0 CG A:GLU72 4.0 3.0 1.0 CA I:VAL38 4.0 8.4 1.0 N A:GLY308 4.1 3.0 1.0 NE2 A:HIS69 4.1 3.0 1.0 NE2 A:HIS196 4.2 3.0 1.0 CD2 A:HIS196 4.3 3.0 1.0 CD2 A:HIS69 4.4 3.0 1.0 CA A:HIS196 4.5 3.0 1.0 O A:SER197 4.6 3.0 1.0 N A:SER197 4.7 3.0 1.0 CA A:GLY308 4.7 4.3 1.0 O A:GLY308 4.8 10.0 1.0 NH2 A:ARG127 4.9 6.2 1.0 C A:GLY308 4.9 9.8 1.0

Zinc binding site 2 out of 2 in the Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn309 b:10.6 occ:1.00 O J:VAL38 1.7 8.2 1.0 OE2 B:GLU72 2.0 18.3 1.0 ND1 B:HIS69 2.2 3.0 1.0 ND1 B:HIS196 2.3 3.0 1.0 CD B:GLU72 2.6 3.0 1.0 OE1 B:GLU72 2.6 19.5 1.0 C J:VAL38 2.7 10.5 1.0 CE1 B:HIS69 2.9 3.0 1.0 CE1 B:HIS196 3.0 3.0 1.0 OXT J:VAL38 3.2 20.4 1.0 CG B:HIS196 3.4 3.0 1.0 CG B:HIS69 3.4 3.0 1.0 CB B:HIS196 3.7 3.0 1.0 CB B:HIS69 3.9 3.0 1.0 CG B:GLU72 4.0 3.0 1.0 CA J:VAL38 4.0 8.4 1.0 N B:GLY308 4.1 3.0 1.0 NE2 B:HIS69 4.1 3.0 1.0 NE2 B:HIS196 4.2 3.0 1.0 CD2 B:HIS196 4.3 3.0 1.0 CD2 B:HIS69 4.4 3.0 1.0 CA B:HIS196 4.5 3.0 1.0 O B:SER197 4.6 3.0 1.0 N B:SER197 4.7 3.0 1.0 CA B:GLY308 4.7 4.3 1.0 O B:GLY308 4.8 10.0 1.0 NH2 B:ARG127 4.9 6.2 1.0 C B:GLY308 4.9 9.8 1.0

D.C.Rees, W.N.Lipscomb. Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 A Resolution. J.Mol.Biol. V. 160 475 1982.
ISSN: ISSN 0022-2836
PubMed: 7154070
DOI: 10.1016/0022-2836(82)90309-6