Atomistry » Zinc » PDB 4ci2-4csa » 4cob
Atomistry »
  Zinc »
    PDB 4ci2-4csa »
      4cob »

Zinc in PDB 4cob: Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa

Enzymatic activity of Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa

All present enzymatic activity of Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa:
3.5.1.9;

Protein crystallography data

The structure of Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa, PDB code: 4cob was solved by L.Diaz-Saez, V.Srikannathasan, M.Zoltner, W.N.Hunter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 97.62 / 2.37
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 112.721, 112.721, 90.761, 90.00, 90.00, 120.00
R / Rfree (%) 15.047 / 19.367

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa (pdb code 4cob). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa, PDB code: 4cob:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 4cob

Go back to Zinc Binding Sites List in 4cob
Zinc binding site 1 out of 4 in the Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:54.2
occ:1.00
OD2 A:ASP56 2.0 38.9 1.0
OE2 A:GLU173 2.2 35.6 1.0
NE2 A:HIS161 2.2 37.0 1.0
O A:HOH2042 2.4 40.2 1.0
OE1 A:GLU173 2.5 34.9 1.0
CD A:GLU173 2.7 36.8 1.0
ZN A:ZN402 3.0 47.3 1.0
CG A:ASP56 3.0 33.1 1.0
CE1 A:HIS161 3.1 34.6 1.0
CD2 A:HIS161 3.3 36.2 1.0
OD1 A:ASP56 3.3 36.5 1.0
O A:HOH2041 3.5 38.6 1.0
O A:HOH2034 3.8 38.1 1.0
CD2 A:HIS60 4.0 37.9 1.0
NE2 A:HIS60 4.1 38.3 1.0
CG A:GLU173 4.2 35.4 1.0
ND1 A:HIS161 4.2 34.7 1.0
CB A:ASP56 4.3 37.7 1.0
OG A:SER149 4.3 36.1 1.0
CG A:HIS161 4.4 32.3 1.0
O A:HOH2037 4.4 56.2 1.0
O A:PRO148 4.7 41.6 1.0
CG2 A:ILE171 4.7 38.4 1.0
NE2 A:HIS54 4.8 36.2 1.0
CA A:SER149 4.8 33.5 1.0
ND1 A:HIS50 4.8 36.5 1.0
N A:LEU150 4.9 35.6 1.0
CB A:SER149 4.9 37.9 1.0
CE1 A:HIS50 5.0 36.9 1.0

Zinc binding site 2 out of 4 in 4cob

Go back to Zinc Binding Sites List in 4cob
Zinc binding site 2 out of 4 in the Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn402

b:47.3
occ:1.00
NE2 A:HIS54 2.2 36.2 1.0
OD1 A:ASP56 2.2 36.5 1.0
OE1 A:GLU173 2.3 34.9 1.0
ND1 A:HIS50 2.3 36.5 1.0
O A:HOH2034 2.4 38.1 1.0
O A:HOH2042 2.6 40.2 1.0
ZN A:ZN401 3.0 54.2 1.0
CE1 A:HIS50 3.1 36.9 1.0
CD2 A:HIS54 3.1 35.0 1.0
CE1 A:HIS54 3.1 38.3 1.0
CG A:ASP56 3.1 33.1 1.0
OD2 A:ASP56 3.4 38.9 1.0
CG A:HIS50 3.4 39.6 1.0
CD A:GLU173 3.5 36.8 1.0
O A:HOH2037 3.9 56.2 1.0
CB A:HIS50 3.9 38.4 1.0
OE2 A:GLU173 4.1 35.6 1.0
ND1 A:HIS54 4.2 38.6 1.0
NE2 A:HIS50 4.3 35.3 1.0
CG A:HIS54 4.3 34.7 1.0
NE2 A:HIS60 4.4 38.3 1.0
O A:PRO148 4.4 41.6 1.0
CD2 A:HIS50 4.5 34.2 1.0
O A:HOH2041 4.5 38.6 1.0
CB A:ASP56 4.5 37.7 1.0
CD2 A:HIS60 4.6 37.9 1.0
CA A:HIS50 4.7 38.8 1.0
CG A:GLU173 4.7 35.4 1.0
CB A:GLU173 4.8 33.4 1.0

Zinc binding site 3 out of 4 in 4cob

Go back to Zinc Binding Sites List in 4cob
Zinc binding site 3 out of 4 in the Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn401

b:74.5
occ:1.00
OD2 B:ASP56 2.1 56.9 1.0
OE2 B:GLU173 2.3 52.7 1.0
NE2 B:HIS161 2.4 63.1 1.0
O B:HOH2028 2.5 48.5 1.0
OE1 B:GLU173 2.8 46.6 1.0
CD B:GLU173 2.9 47.4 1.0
ZN B:ZN402 2.9 53.9 1.0
CG B:ASP56 3.1 52.2 1.0
CE1 B:HIS161 3.3 54.7 1.0
OD1 B:ASP56 3.3 41.5 1.0
O B:HOH2023 3.4 43.3 1.0
CD2 B:HIS161 3.4 59.9 1.0
NE2 B:HIS60 3.8 58.8 1.0
CD2 B:HIS60 3.9 56.1 1.0
CG B:GLU173 4.4 41.4 1.0
OG B:SER149 4.4 52.3 1.0
ND1 B:HIS161 4.4 62.4 1.0
CB B:ASP56 4.5 50.2 1.0
CG B:HIS161 4.5 62.2 1.0
O B:PRO148 4.6 51.5 1.0
ND1 B:HIS50 4.6 45.3 1.0
CE1 B:HIS50 4.7 41.3 1.0
NE2 B:HIS54 4.8 45.0 1.0
O B:HOH2026 4.8 56.9 1.0
CA B:SER149 4.8 46.0 1.0
CB B:SER149 4.8 47.2 1.0
CG2 B:ILE171 4.8 44.7 1.0

Zinc binding site 4 out of 4 in 4cob

Go back to Zinc Binding Sites List in 4cob
Zinc binding site 4 out of 4 in the Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure Kynurenine Formamidase From Pseudomonas Aeruginosa within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn402

b:53.9
occ:1.00
NE2 B:HIS54 2.2 45.0 1.0
O B:HOH2023 2.2 43.3 1.0
OE1 B:GLU173 2.2 46.6 1.0
OD1 B:ASP56 2.2 41.5 1.0
ND1 B:HIS50 2.2 45.3 1.0
ZN B:ZN401 2.9 74.5 1.0
CE1 B:HIS50 2.9 41.3 1.0
CD2 B:HIS54 2.9 39.7 1.0
CG B:ASP56 3.2 52.2 1.0
CE1 B:HIS54 3.3 43.1 1.0
O B:HOH2028 3.4 48.5 1.0
OD2 B:ASP56 3.4 56.9 1.0
CD B:GLU173 3.4 47.4 1.0
CG B:HIS50 3.5 47.9 1.0
OE2 B:GLU173 3.9 52.7 1.0
CB B:HIS50 4.0 50.3 1.0
CG B:HIS54 4.1 38.7 1.0
NE2 B:HIS50 4.1 44.8 1.0
ND1 B:HIS54 4.3 45.0 1.0
O B:HOH2026 4.3 56.9 1.0
NE2 B:HIS60 4.4 58.8 1.0
CD2 B:HIS50 4.4 42.9 1.0
O B:PRO148 4.4 51.5 1.0
CB B:ASP56 4.6 50.2 1.0
CA B:HIS50 4.6 51.5 1.0
CG B:GLU173 4.7 41.4 1.0
CD2 B:HIS60 4.7 56.1 1.0
CB B:GLU173 4.9 38.7 1.0
CE1 B:HIS60 5.0 49.1 1.0

Reference:

L.Diaz-Saez, V.Srikannathasan, M.Zoltner, W.N.Hunter. Structure of Bacterial Kynurenine Formamidase Reveals A Crowded Binuclear-Zinc Catalytic Site Primed to Generate A Potent Nucleophile. Biochem.J. V. 462 581 2014.
ISSN: ISSN 0264-6021
PubMed: 24942958
DOI: 10.1042/BJ20140511
Page generated: Wed Dec 16 05:08:54 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy